Tei指数评价川崎病患儿心脏功能的临床意义  

Evaluation of myocardial function impairment using the Tei index in patients with Kawasaki disease

作　　者：李梅[1,2] 刘俊琪[1,2] 张晓蓉[1,2] 薛利芳[1,2] 

机构地区：[1]北京市海淀医院 [2]北京大学第三医院海淀院区超声科,100089

出　　处：《武警医学》2014年第7期681-684,共4页Medical Journal of the Chinese People's Armed Police Force

摘　　要：目的应用Tei指数评价川崎病(kawasaki disease,KD)患儿心脏功能,探讨其临床意义。方法超声心动图测量KD急性期和恢复期患儿62例的左室射血分数(EF)、左室短轴缩短率(FS)、二尖瓣口舒张期血流E/A比值、肺静脉血流S/D比值、左右心室等容收缩期(ICT)、等容舒张期(IRT)、射血时间(ET)和计算左、右心室Tei指数,并与80例年龄、性别匹配的健康儿童作比较。结果 KD急性期左心室Tei指数较健康儿童明显增高(0.43±0.07 vs 0.37±0.06,P<0.01),恢复期组左心室Tei指数减低,接近健康儿童(0.40±0.09 vs 0.37±0.06),差异无统计学意义;KD急性期右心室Tei指数增加,与健康对照组相比差异有统计学意义(0.31±0.06 vs 0.25±0.05,P<0.01),恢复期组右心室Tei指数减低,逐渐接近正常(0.30±0.08 vs 0.25±0.05),差异无统计学意义。结论 KD急性期患儿存在心脏整体功能异常,Tei指数能准确、敏感地评价患儿心脏整体功能。Objective To investigate the clinical value of Tei index in the myocardial function in patients with Kawasaki dis -ease（KD）.Methods In the prospective study, 50 patients underwent echocardiogramphic evaluation .The left ventricular ejection fraction （EF）, shortening fraction （FS）, peak E/A ratio at mitral valve （E/A）, peak S/D ratio of pulmonary venous flow （S/D）, isovolumetric continuaction time （ICT）, isovolumetric relaxation time （IRT） and ejection time （ET） were measured.Tei index was calculated.As a control, we also assessed 72 healthy children, matched for age and sex with the study population .Results Compared with the control group , left ventricular Tei index was significantly increased in the children with acute KD guoup （0.44 ±0.07 vs 0.37 ±0.05,P〈0.01）.Tei index of KD group in convalescent stage was decreased （0.40 ±0.09 vs 0.37 ±0.05, P〉0.05）.Right ven-tricular Tei index was also significantly increased in the children with acute KD guoup （0.44 ±0.07 vs 0.37 ±0.05,P〈0.01） com-pared with the healthy children .And during the convalescent stage , the right ventricular Tei index tended to normal .Conclusions The ventricular global function was impaired in children with acute KD .Tei index is a accurate and sensitive tool for estimating global myocardial dysfunction in KD patients .

关 键 词：TEI指数 多普勒 川崎病 心脏整体功能损害 

分 类 号：R445.1[医药卫生—影像医学与核医学]