木糖氧化无色杆菌皮肤及软组织感染7例分析  

Analysis of Achromobacter xylosoxidans infection in skin and soft tissue of seven patients

作　　者：王伟宝 王建芳 谢飞 牛淑丽 王智霞 

机构地区：[1]张家口市第四医院检验科,河北张家口075000

出　　处：《中国热带医学》2014年第7期882-883,898,共3页China Tropical Medicine

摘　　要：目的探讨木糖氧化无色杆菌导致的皮肤及软组织感染病例的临床特征及临床分离株的耐药性。方法对2007年3月~2014年2月间张家口市第四医院检出的7例木糖氧化无色杆菌皮肤及组织感染患者临床资料进行回顾性分析。结果 7例木糖氧化无色杆菌皮肤及组织感染患者中,6例(85.7%)患者感染继发于创伤、近期手术及心血管疾病;5例(71.4%)患者为木糖氧化无色杆菌单独感染;4例(57.1%)患者为社区获得性感染;除1例感染复发外,其它患者使用抗生素进行治疗后临床转归都较好。结论木糖氧化无色杆菌可引起社区获得性感染,引发皮肤及软组织感染,尤其是有心血管疾病、近期手术史及创伤的患者。木糖氧化无色杆菌高抗生素抵抗能力,治疗方法存在区别,需谨慎考虑抗生素的选择及患者的基础病情。Objective To discuss the clinical characteristics of Achromobacter xylosoxidans infections in skin and soft tissue of seven patients. Methods The clinical data of 7 cases infected with Achromobacter xylosoxidans in the skin and soft dssue in Zhangjiakou Municipal Fourth People＇ s Hospital from March 2007 to February 2014 were retrospectively analyzed. Results Six patients （85.7%） were secondarily infected due to trauma, recent surgery and vascular diseases; 5 patients （71.4%） were only infected with Achmmobacter xy]osoxida^s and 4 patients （57.1%） were due to community-acquired infection. The clinical outcome of the patients was relatively good after treated with antibiotics, except a patients who suffered from recurrence of the infection. Conclusion Achromobacter xylosoxidans can cause community-acquired infection and infect the skin and soft tissue, especially in patients with trauma, after surgery or vascular diseases. Caution is indicated in selection of antibiotics for treatment of cases infected with Achromobacter xylosoxidans highly resistant to antibiotics.

关 键 词：木糖氧化无色杆菌 产碱杆菌属 皮肤感染 软组织感染 耐药性 

分 类 号：R378[医药卫生—病原生物学]