美罗培南治疗脑肿瘤术后颅内细菌感染效果分析  

Analysis of efficacy of meropenem in treatments of intracranial infection after brain tumor operation

作　　者：王加充[1] 王鹏程[1] 徐晓云[2] 

机构地区：[1]海南省人民医院神经外科,海南海口570311 [2]海南省人民医院药学部,海南海口570311

出　　处：《中国热带医学》2014年第7期903-904,共2页China Tropical Medicine

摘　　要：目的比较美罗培南不同输注方式治疗脑肿瘤术后颅内感染的临床效果。方法回顾分析83例脑肿瘤术后颅内感染应用不同方式输注美罗培南治疗的患者,其中微量泵静脉持续输注组39例,传统间断输注组44例。比较两组的用药3d后出现头痛缓解率、体温好转比率、脑脊液糖定量达到正常比率、平均用药疗程及平均住院天数。结果用美罗培南后体温的控制、脑脊液糖定量检测,微量泵静脉持续输注组优于间断输注组(P<0.05)。持续输注组的平均用药疗程及平均住院天数较传统间断输注组缩短(P<0.05)。结论在美罗培南治疗脑肿瘤术后颅内感染的方案中,微量泵静脉持续输注方式明显优于间断输注方式。Objective . To analyze the efficacy of meropenem in treatmeni of intracranial infection after brain tumor operation. Methods The efficacy of meropenem on 83 brain tumors cases complicated with intracrartial infection were divided into Group A （39 cases）received meropenem by Continuously intravenous micro-pump infusion and Group B （44 cases） treated by classical intermittent infusion.. Results After treatmentwith meropenem the reduction of temperature and levels of CSF glucose, in cases of Group A was better compared with those in Group B （P〈0.05）. The average duration of course and the days Of hospitalization of cases in Group .P~ were ish0rter icompared tO that of Group B （P〈0.05）.Conclusion Meropenem administered by intravenous micro-pump infusion is effective for treatment~ of brain tumor cases complicated with intracranial infection.

关 键 词：美罗培南 静脉持续输注 颅内感染 

分 类 号：R978.1[医药卫生—药品]