芬吗通联合坤泰胶囊在体外受精-胚胎移植卵巢低反应患者中的应用  

Application of femoston combined with Kuntai capsule in poor ovarian responders receiving vitro fertilization

作　　者：李巍巍[1] 安丽红[1] 张歌[1] 王兴玲[1] 孙丽君[1] 管一春[1] 娄华[1] 袁恩武[1] 

机构地区：[1]河南省郑州大学第三附属医院生殖医学科,450052

出　　处：《实用医学杂志》2014年第14期2308-2310,共3页The Journal of Practical Medicine

摘　　要：目的:探讨芬吗通联合坤泰胶囊在体外受精-胚胎移植(IVF-ET)卵巢低反应(POR)患者中的应用。方法:选取在郑州大学第三附属医院生殖医学科行IVF中的POR患者,随机筛选120例,进入第二周期助孕前,行芬吗通联合坤泰胶囊预处理3个月经周期,行自身对照,比较卵泡刺激素(FSH)、促黄体生成素(LH)、雌二醇(E2)、抗苗勒管激素(AMH)、窦卵泡数、动脉收缩期峰值流速(PSV)、促性腺激素(Gn)用量及天数、HCG日E2值、获卵数、受精率、优质胚胎数、周期取消率的差异。结果:经预处理,患者的FSH、LH水平降低,AMH、PSV水平增加、HCG日E2值、窦卵泡数、获卵数、受精率、优质胚胎数均增加,周期取消率降低,差异具有统计学意义(P<0.05)。结论:芬吗通联合坤泰胶囊的治疗可提高POR患者卵巢储备功能,改善IVF结局。Objective To investigate application of femoston combined with Kuntai capsule in poor ovarian responders （PORs） receiving vitro fertilization. Methods 120 women with poor ovarian response after receiving IVF were s randomly elected. Pre-treatment with femoston plus Kuntai capsule was used for three menstrual cycles before the next cycle of assisted reproductive treatment. FSH, LH, E2, AMH, number of antral follicles, PSV, days of Gn, ampoules of Gn, cycle cancellation rate, E2 value of the day of HCG, follicle of less than 16mm, number of oocytes, fertilization rate, and number of good quality embryos were compared before and after treatment used. Results After pre-treatment, levels of FSH and LH were decreased, AMH, PSV were increased, E2 value of the day of HCG, number of antral follicles, follicle of less than 16 mm, oocytes, fertilization rate, and good quality embryos were increased; cycle cancellation rate was decreased, with significant differences （P〈 0.05）. Conclusions Femoston combined with kuntai capsule can effectively increase the functional reserve of the ovarian in poor ovarian responders, and can improve the outcome of IVF.

关 键 词：卵巢低反应 芬吗通 坤泰胶囊 微刺激 

分 类 号：R714.8[医药卫生—妇产科学]