我院207例药物不良反应报道分析  

Analysis of 207 ADR cases reports in our hospital

作　　者：李予雯[1] 钟洪兰[1] 李祥[1] 邢贞建[1] 

机构地区：[1]广州市胸科医院药剂科,广东广州510095

出　　处：《中国现代医生》2014年第21期39-40,43,共3页China Modern Doctor

摘　　要：目的 检查我院抗结核药不良反应（ADR）的发生情况,了解我院ADR的发生特点,为临床结核病的合理用药提供参考.方法 采用回顾性和描述性研究方法,对我院2010～2012年收集的207例结核药ADR报道进行统计、分析.结果 207例ADR事件以男性患者为主（57.49％）,服用口服药的占55.07％,主要是抗结核药和抗菌药引起ADR,引起的ADR以皮肤及其附件为主（38.28％）,其次为肝肾功能损害和全身反应;严重的ADR 7例（3.5％）;大部分ADR都有较好的转归.结论 临床用药引起的ADR较多,势必会影响患者的依从性,临床应重视ADR并及时发现和治疗,以取得更好的临床效果.Objective To investigate the features of adverse drug reactions （ADR） occurred in our hospital and gave some advises for a better using of drugs. Methods By restrospective and descriptive study, a total of 207 ADR case reports which collected in our hospital from 2010-2012 were analyzed statistically. Results Among 207 ADR reports, 57.49% of ADR patients were man, 55.07% drugs were took orally, the most common ADR was the lesions of skin and appendents （38.28%）, followed by damage of liver/kidney and systemic; there were 7 severe ADR reports （3.5%）; most ADR patients were well healed. Conclusion Many ADRs were caused in clinical, patients＇ compliance could be weakened by those ADR, in this way, found and treat ADR in time have a great significance for treatment.

关 键 词：药品不良反应 监测 报道 

分 类 号：R969.3[医药卫生—药理学]