超高效液相色谱-串联质谱法测定水中痕量双酚A  

Determination of Bisphenol A in Water Samples by Ultra Performance Liquid Chromatography Tandem Mass Spectrometry

作　　者：郁蕾[1] 尹燕敏[1] 顾海东[1] 秦宏兵[1] 

机构地区：[1]苏州市环境监测中心站,江苏苏州215004

出　　处：《环境监测管理与技术》2014年第2期37-38,共2页The Administration and Technique of Environmental Monitoring

基　　金：江苏省环保科研课题基金资助项目(201128);江苏省环境监测基金资助项目(1006)

摘　　要：采用超高效液相色谱-串联质谱法测定水中痕量双酚A,水样经预处理后,以BEH C18超高效液相色谱柱分离,在质谱电喷雾离子源负离子多反应监测模式下测定。方法在0.200μg/L^10.0μg/L范围内线性良好,相关系数r为0.999 2,方法检出限为0.06μg/L,空白及实际样品加标回收率为87.4%~114%,RSD为3.6%~7.4%。A rapid analytical method tor determination of bisphenol A （BPA） in water samples was developed. Water samples were pretreated and then analyzed by ultra pertormance liquid chromatography electrospray tandem mass spectrometry （UPLC-MS/MS） in muhiple reaction monitoring mode via negative electrospray ionization with BEH C18 column（1.7 μm,2.1 mm × 50 mm）using acetonitrile and water as mobile phase in a gradi- ent elution mode. The limit of determination was 0.06 μg/L. The average recoveries of blanks and real samples were at the range of 87.4% - 114% for the spiked levels of 0. 200 μg/L and 10.0 μg/L. The relative standard deviations （RSDs） of spiked samples （n=6） were at the range of 3.6% -7.4%.

关 键 词：双酚A 超高效液相色谱-串联质谱法 水质 

分 类 号：O657.63[理学—分析化学]