司机职业对男性精子DNA完整性的影响分析  

Analysis of the infl uence of driving occupation on male sperm DNA integrity

作　　者：王琛[1,2] 刘安娜[1,2] 王厚照[1,2] 

机构地区：[1]中国人民解放军第一七四医院检验科 [2]厦门大学附属成功医院,福建厦门361003

出　　处：《中国优生与遗传杂志》2014年第8期130-130,67,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨司机职业对男性精子DNA完整性的影响。方法选择91例司机职业的男性不育患者为司机组，根据驾龄分为2组：A组驾龄1～10年，B组驾龄大于10年。对照组为117例非司机职业的健康正常男性，对其进行精子DNA完整性检测。结果司机组内A组精子DNA碎片指数（DFI）与正常对照组比较差异有显著性（P〈0．05），而司机组内B组精子DNA碎片指数（DFI）与正常对照组比较差异有非常显著性（P〈0．01）。结论司机职业会对男性精子DNA完整性产生一定的影响，长期开车可能是引起男性不育的原因之一。Objective： To explore the influence of driving occupation on male sperm DNA integrity. Methods： 91 drivers suffering infertility were named driver group and which was subdivide into group A （1-10 years） and group B （greater than 10years） based on their years of driving experience. 117 normal healthy men were recruited as control. Integrity of sperm DNA in each group was determined. Results： There was a significant difference in sperm DNA fragmentation index （DFI） between group A and control group （P〈0.05） , while a larger significant difference in sperm DNA fragmentation index （DFI） was observed between group B and control group （P〈0.01） . Conclusion： Driving has a certain effect on the sperm DNA integrity and long time driving might be a cause of male infertility.

关 键 词：司机职业 精子DNA完整性 男性不育 

分 类 号：R698.2[医药卫生—泌尿科学]