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作 者:王红玲[1] 徐桂芳[1] 苗丽燕[1] 韩征利[1]
出 处:《中国煤炭工业医学杂志》2014年第8期1314-1317,共4页Chinese Journal of Coal Industry Medicine
摘 要:目的探讨雾化吸入联合胸部物理治疗在儿童哮喘急性发作期中的临床疗效观察。方法选择处于哮喘急性发作期的患儿60例,均不具备细菌感染指征,随机分为对照组、雾化组和护理组,每组各20例。对照组给予静脉应用甲泼尼龙、氨茶碱及雾化吸入沙丁胺醇治疗;雾化组给予雾化吸入布地奈德和沙丁胺醇;护理组在雾化吸入布地奈德和沙丁胺醇结束后给予胸部物理治疗。比较三组患儿治疗后肺部症状和体征、FEV1%(FEV1实测值/预计值百分比)、治疗天数及治疗效果有无差异。结果三组间喘憋、咳嗽症状、肺部哮鸣及啰音消失所需时间及FEV1%、治疗天数方面比较差异无统计学意义(P>0.05);三组临床疗效比较差异无统计学意义(P>0.05)。结论治疗非感染因素诱发的儿童哮喘急性发作,规律有效的雾化吸入布地奈德和沙丁胺醇,结合胸部物理治疗,能达到与常规静脉应用甲泼尼龙、氨茶碱相似的治疗效果,值得临床推广应用。Objective To explore the clinical curative effect of atomization inhalation and chest physical therapy in children during asthma acute attack. Methods Sixty children with acute attack of asthma but without bacterial infection were randomized divided into control group, atomization group and nursing group(twenty cases each group). Control group was given intravenous injection of methyl prednisolone, aminophylline and atomizing inhaled albuterol; atomization group was given atomizing inhaled budesonide and salbutamol; nursing group was given chest physiotherapy after inhalation of budesonide and salbutamol. The difference of pulmonary symptoms and signs, the ratio of forced expiratory volume in one second (measured values/expected value) and treatment days, curative effect were compared with each other after treatment. Results There were no significant difference in the disappearance time of dyspnoea, cough, pulmonary wheeze and tales among three groups (P〉0.05); There was no significant difference in the clinical curative effect among them(P〉0.05). Conclusions Regular and effective inhalation of budesonide and salbutamol combined with chest physiotherapy given to asthmatic children without bacterial infection during acute attack episode has the similar clinical effect to using methyl prednisolone and aminophylline, which is worthy of carrying out in clinic.
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