新生儿窒息血常规结果分析及其临床意义  

Analysis of Blood Routine Examination for Asphyxia Neonatorum and Its Clinical Significance

作　　者：常正义[1] 马迎教[2] 潘云[1] 陈碧艳[3] 曾冬云[1] 

机构地区：[1]右江民族医学院附属医院检验科,百色市533000 [2]右江民族医学院预防医学教研室,百色市533000 [3]广西百色市妇幼保健院检验科,百色市533000

出　　处：《广西医学》2014年第9期1240-1242,共3页Guangxi Medical Journal

基　　金：广西百色市科学研究与技术开发计划项目(20110506)

摘　　要：目的探讨新生儿窒息血常规29项参数的变化及其临床意义。方法利用Sysmex XE-5000全自动血细胞分析仪对新生儿窒息40例(窒息组)和正常新生儿38例(对照组)进行白细胞、红细胞及血小板等参数检测,分析其结果和临床意义。结果 (1)白细胞参数:窒息组中性粒细胞比率明显高于对照组(P<0.05),淋巴细胞比率、单核细胞比率明显低于对照组(P<0.05),白细胞计数、嗜酸性粒细胞比率、嗜碱性粒细胞比率比较,差异无统计学意义(P>0.05)。(2)红细胞参数:窒息组红细胞平均血红蛋白浓度、低荧光网织红细胞比率明显低于对照组(P<0.05),红细胞分布宽度CV、红细胞分布宽度SD、网织红细胞计数、网织红细胞百分比、未成熟网织红细胞百分比、高荧光网织红细胞比率、有核红细胞计数、有核红细胞百分比明显高于对照组(P<0.05);两组红细胞计数、血红蛋白、红细胞压积、红细胞平均体积、红细胞平均血红蛋白含量、中荧光网织红细胞比率、网织红细胞血红蛋白含量比较,差异无统计学意义(P>0.05)。(3)血小板参数:窒息组血小板计数、血小板压积明显低于对照组(P<0.05);两组平均血小板体积、血小板分布宽度、大型血小板比率及未成熟血小板指数比较,差异无统计学意义(P>0.05)。结论动态监测患儿血常规可以及时了解窒息患儿病情的变化,对新生儿窒息初步筛查、判定严重程度、早期干预及救治具有重要意义。Objective To investigate the changes of the 29 parameters of blood routine in asphyxia newborns,and to study the clinical significance. Methods The automatic blood cell analyzer Sysmex XE-5000 was used to analyze the parameters,such as leukocytes,erythrocytes and platelets in 40 asphyxia newborns（ asphyxia group） and 38 normal newborns（ control group）. The results and clinical significance were analyzed as well. Results （1） The parameters of leukocytes： The neutrophil ratio（ NEUT%） was significantly higher（ P〈0. 05）,the lymphocyte ratio（ LYMPH%） and monocyte ratio（ MONO%） were significantly lower in the asphyxia group in contrast with those in the control group（ P〈0.05）. The WBC count,eosinophil ratio（ EO%） and basophils ratio（ BASO%） showed no significant difference between two groups（ P〉0. 05）. （2） The parameters of erythrocytes： The mean hemoglobin concentration（ MCHC） and low fluorescent reticulocyte percentage in the asphyxia group were significantly lower than those in the control group（ P〈0. 05）.The red blood cell distribution width CV（ RDW-CV）,red blood cell distribution width SD（ RDW-SD）,reticulocyte count（ RET）,percentage of reticulocytes（ RET%）,percentage of immature reticulocyte（ IRF）,high fluorescence reticulocyte ratio（ HFR）,nucleated red blood cell count（ NRBC） and percentage of nucleated red blood cell（ NRBC%） in the asphyxia group were significantly higher than those in the control group（ P〈0. 05）. No significant differences were found in the red blood cell count,hemoglobin,hematocrit,mean corpuscular volume（ MCV）,content of mean corpuscular hemoglobin（ MCH）,ratio of median fluorescence reticulocytes（ MFR） and content of hemoglobin in reticulocytes（ RET-He） between two groups（ P〈0. 05）. （3） The parameters of platelets： The platelet count（ PLT） and plateletcrit（ PCT） in the asphyxia group were significantly lower than those in the control group（ P〈0. 05�

关 键 词：新生儿窒息 血常规 白细胞 红细胞 血小板 

分 类 号：R727.12[医药卫生—儿科]