持续阴道超声辐射后人胚早孕绒毛细胞超微结构的变化研究  

Study on changes of persistent vaginal ultrasound radiation on human embryonicvilli ultrastructure

作　　者：陈玉阁[1] 孟军[1] 王海鹰[1] 杨玉[1] 

机构地区：[1]深圳市蛇口人民医院妇产科,广东深圳518000

出　　处：《海南医学》2014年第13期1927-1928,共2页Hainan Medical Journal

基　　金：广东省深圳市科技局立项(编号:201002175)

摘　　要：目的探究持续阴道超声辐射后人胚早孕绒毛细胞超微结构的变化。方法选取我院2010年9月至2012年3月期间进行人流的早孕患者80例，将其均分为两组，试验组患者阴道超声照射10min，而对照组患者则照射5min，然后在照射后24-30h进行人流并取绒毛组织进行检测，比较两组患者照射后绒毛组织DNA及其超微结构的变化情况。结果经过检测得到，试验组患者的绒毛组织单链DNA量为（0．19±0．06）μg／μl，双链DNA量为（0．15±0．09）μg／μl，明显低于对照组患者的（0．23±0．07）μg／μl和（0．19±0．07）μg／μl，差异均具有统计学意义（P〈0．05），试验组患者的绒毛组织超微结构发生异常者40．00％，对照组为10．00％，差异也具有统计学意义（P〈0．05）。结论降低患者进行阴道超声辐射的时间可以减少患者绒毛细胞超微结构的改变。Objective To explore the human embryonic villi ultrastructure changes by persistent vaginal ultrasound radiation. Methods Eighty cases of induced abortion in our hospital from Sep. 2010 to Mar. 2012 were selected as the study objects and divided into two groups, vaginal ultrasound radiation was performed in experimental group patients for 10 minutes, while the control group was irradiated for 5 minutes, after 24 to 30 hours of irradiation, induced abortion was adopted in two groups and detected their pile weave, pile weave DNA and changes of ultrastruc- ture after irradiation in two groups were compared. Results After detecting, it showed that the ssDNA of pile weave of experimental group was （-0.19±0.06）, dsDNA was （0.15±0.09）, which were significantly lower than control group （0.23±0.07） and （0.19±0.07）], differences between two groups were statistically significant （P〈0.05）; in experimental group, the incidence of abnormal ultrastructure in pile weave was 40.00%, while in control group was 10.00%, difference was statistically significant （P〈0.05）. Conclusion It can reduce the changes ofultrastructure in pile weave that lower the time of vaginal ultrasound radiation.

关 键 词：持续阴道超声辐射 人胚早孕绒毛细胞 超微结构 变化 

分 类 号：R714.12[医药卫生—妇产科学]