初诊2型糖尿病患者血清超敏C反应蛋白水平及相关因素分析  

Study of Levels and Related Factors of Serum High Sensitivity C-reactive Protein in Newly Diagnosed Type 2 Diabetic Patients

作　　者：黄艳芳 胡孝海[2] 

机构地区：[1]广东省深圳市龙华新区人民医院龙胜社康,广东深圳518000 [2]广东省深圳市坪山新区人民医院急诊科,广东深圳518000

出　　处：《河北医学》2014年第10期1619-1621,共3页Hebei Medicine

基　　金：广东省深圳市龙岗区科技计划项目;(编号:YS2013117)

摘　　要：目的:探讨初诊2型糖尿病患者血清超敏C反应蛋白水平及相关因素。方法:选择50例初诊2型糖尿病患者及50例健康体检者作为研究对象,比较两组患者血清hs-CRP水平,并分析2型糖尿病患者hs-CRP相关因素。结果:初诊2型糖尿病患者BMI、腰围、SBP、DBP、TC、TG及hsCRP水平均明显高于健康对照组,差异有统计学意义(P<0.05);2型糖尿病患者BMI、腰围、FBG、HOMA-IR与血清CRP水平呈正相关性(P<0.05),HOMA-B与血清CRP水平呈负相关性(P<0.05)。结论:血清hs-CRP水平在初诊2型糖尿病患者明显升高,可能与超重或肥胖及胰岛素抵抗、胰岛β细胞功能衰退相关。Objective：To investigate levels and related factors of serum high sensitivity C-reactive pro-tein（hs-CRP） in newly diagnosed type 2 diabetic patients.Method：50 cases of newly diagnosed type 2 di-abetic patients and 50 healthy volunteers were included in this study , the serum hs-CRP levels in two groups and hs-CRP relevant factors in type 2 diabetes were analyzed.Result：The BMI, waist circumference ,SBP, DBP,TC,TG and hs-CRP in patients with type 2 diabetes were significantly higher than those in control group, the difference was statistically significant （ P〈0.05）; In type 2 diabetes patients ,the BMI, waist circumference , FBG, HOMA-IR and serum CRP levels were of positively connection （ P〈0.05） , HOMA-B and serum CRP levels was of negatively connection （ P 〈0.05） .Conclusion：The serum hs-CRP levels are significantly elevated in patients with newly diagnosed type 2 diabetes , and may be associated with over-weight or obesity and insuLin resistance , pancreatic B-cell function decline .

关 键 词：2型糖尿病 炎症因子 胰岛素抵抗 

分 类 号：R587.1[医药卫生—内分泌]