响应面分析法优化茵陈中总黄酮的提取工艺  

Optimization of the Extraction Technology of Total Flavonoids from Artemisia Capillaris Herba by Response Surface Methodology

作　　者：宋海[1,2] 吴冬青[1,2] 安红钢[1,2] 林敏[1,2] 任雪峰[1,2] 

机构地区：[1]河西学院化学化工学院,甘肃张掖734000 [2]甘肃省高校河西走廊特色资源利用省级重点实验室,甘肃张掖734000

出　　处：《食品研究与开发》2014年第11期65-69,共5页Food Research and Development

基　　金：甘肃省教育厅(1109B-07)资助项目;河西学院青年基金(QN2011-21)资助项目

摘　　要：在单因素试验的基础上,利用响应面分析法优化茵陈总黄酮的提取工艺。确定茵陈总黄酮的最佳提取工艺条件为:料液比为1∶73(g/mL),乙醇浓度为77%,提取时间为1.68h(100min),提取温度为71℃。在此条件下,茵陈总黄酮的提取率为7.920%,与预测值7.962%相差0.53%。说明该优化方法合理可行。On the basis of single factor experiment,response surface methodology was applied to optimize the extraction conditions of total flavonoids from Artemisia Capillaris Herba. The results showed that the optimal extraction condition was as follows：solid to solvent ratio was 1∶73 （g/mL）, concentration of ethanol was 77%, extraction time was 1.68 h and extraction temperature was 71℃. Under these conditions, the measured extraction rate of flavonoids was 7.920%, compared with the predictive value of 7.962%, the relative error was-0.53%. The result show it is feasible to adopt response surface methodology to optimize the extraction condition.

关 键 词：茵陈 总黄酮 响应面试验 提取工艺 

分 类 号：TQ461[化学工程—制药化工]