气相色谱法测定西黄滴丸中麝香酮和乙酸辛酯的含量  

Determination of Musk Ketone and Octyl Acetate in Xihuang Dripping Pills through Gas Chromatography

作　　者：吴超[1] 李峰[1] 朱晓静[1] 丛晓娟 

机构地区：[1]山东中医药大学,山东济南250355

出　　处：《山东中医杂志》2014年第7期578-580,共3页Shandong Journal of Traditional Chinese Medicine

基　　金：国家(山东)创新药物孵化基地项目(编号:2010ZX09401-302-1-13)

摘　　要：目的：用气相色谱法测定西黄滴丸中麝香酮和乙酸辛酯的含量。方法：Agilent 19091S-433毛细管柱，程序升温，进祥口温度230℃．检测器温度250℃。结果：麝香酮浓度在8．75-140．00μg／mL范围内线性良好（r=0．9998），平均回收率为99．95％，RSD为1．03％：乙酸辛酯浓度在0．0325-0．6000mg／mL内线性良好（r=0．9999），平均回收率为99．78％，RSD为1．33％。结论：本方法可准确测定西黄滴丸中麝香酮和乙酸辛酯的含量。Objective：To determine musk ketone and octyl acetate in the Xihuang dripping pills through Gas Chromatography（GC）. Methods：Capillary column of Agilent 19091S-433 （30m×0.25mm ×0.25μm） was used. The injector temperature was 230 ℃ with programmed temperature. The detector temperature was 250 ℃. Results：The linearity of musk ketone was good in the ranges of 8.75～140μg/mL（r=0.9998）. The average recoveries rate were 99.95% （RSD of 1.03%）. The linearity of octyl acetate was good in the ranges of 0.0325～0.6 mg/mL（r=0.9999）. The average recoveries rate were 99.78% （RSD 1.33%）. Conclusion ：The method is accurate and suitable for determination of musk ketone and octyl acetate in Xihuang dripping pills.

关 键 词：气相色谱法 西黄滴丸 麝香酮 乙酸辛酯 

分 类 号：R284.2[医药卫生—中药学]