七氟醚和氨氟醚低流量麻醉在临床麻醉应用中的效果比较  

作　　者：吴昊 

机构地区：[1]湘乡市人民医院,湖南411400

出　　处：《当代医学》2014年第23期47-48,共2页Contemporary Medicine

摘　　要：目的：分析七氟醚和氨氟醚低流量麻醉在临床麻醉应用中的效果比较。方法选取2010年3月～2013年3月在湘乡市人民医院行美国麻醉医师协会（ASA）Ⅰ～Ⅱ级择期腹部外科手术患者124例，随机均分为七氟醚组和氨氟醚组（n=62）。所有患者经麻醉诱导后行气管插管，再使患者与麻醉机相连。七氟醚组吸入七氟醚来麻醉维持，气体流速为0.8～1.0 L/min，氨氟醚组吸入氨氟醚来麻醉维持，气体流速为0.3～0.5 L/min，麻醉维持过程中保持1.9%的七氟醚浓度和1.7%的氨氟醚浓度。记录患者拔管时间、睁眼时间、正确回答姓名时间、正确回答生日时间、发生躁动的例数、发生恶心呕吐的例数。结果七氟醚组患者的睁眼时间与氨氟醚组比较，差异有统计学意义（P＜0.05）；其中，七氟醚组合安氟醚组的拔管时间（min）、睁眼时间（min）、回答姓名时间（min）和回答生日时间（min）分别为：（14.67±3.85）、（6.72±3.21）、（18.32±3.62）和（19.07±8.86）以及（15.54±4.08）、（20.86±5.37）（、19.89±6.85）和（21.64±8.75）。七氟醚组患者的躁动发生率、恶心呕吐发生率（9.68%和4.84%）与氨氟醚组（25.81%和20.97%）比较，差异有统计学意义（P＜0.05）。结论七氟醚的麻醉效果优于氨氟醚，具有麻醉诱导快、对呼吸道刺激作用小、苏醒时间短、不良反应发生率低等特点。Objective To compare the side effects of sevolfurane and enlfurane in low-lfow anesthesia in clinical applications. Methods 124 patients were selected who carried ASAⅠtoⅡgrade abdominal surgery in the hospital from March 2010 to March 2013, randomly divided into sevolfurane group and enlfurane group, 62 cases in each group. All patients underwent endotracheal intubation after induction of anesthesia, and then connected the patient with anesthesia machine. Sevolfurane group inhalation sevolfurane to anesthetic maintain, the gas lfow rate was 0.8-1.0 L/min,enlfurane group inhalation enlfurane to anesthesia maintenance, the gas lfow rate was 0.3-0.5 L/min,anesthesia maintenance process to maintain 1.9%sevolfurane concentration and 1.7%enlfurane concentration. Recorded extubation time, eye opening time, the time of answer name correct, the time of answer birthday correct, the number of occurring restlessness cases, the number of occurring nausea and vomiting cases. Results Time to eye opening in sevolfurane group and enlfurane group had statistically signiifcant difference （P〈0.05）;Sevolfurane combination of enlfurane group of decannulation time （min）, open time （min）, answer name time （min） and answer the birthday time （min）, respectively：14.67±3.85, 6.72±3.21, 18.32±3.62 and 19.07±8.86 and 15.54±4.08, 20.86±5.37 and 19.89±6.85 and 21.64±8.75. Sevolfurane group of patients with agitation rate, incidence of nausea and vomiting （9.68%and 4.84%） and ammonia deslfurane group （25.81%and 20.97%）. Conclusion Sevolfurane anesthesia effect is better than enlfurane,it has the characteristics of fast induction of anesthesia, respiratory tract irritation small, short recovery time and low incidence of adverse reactions.

关 键 词：七氟醚 氨氟醚 低流量麻醉 

分 类 号：R614[医药卫生—麻醉学]