综合ICU患者多药耐药菌感染分析  

Analysis of multi-drug resistant infections in general ICU

作　　者：袁智慧[1] 何勤 陈毅 袁静 

机构地区：[1]重庆市第五人民医院ICU重症医学科,重庆400062 [2]重庆市长寿区人民医院ICU重症医学科,重庆401220

出　　处：《中华医院感染学杂志》2014年第15期3679-3681,共3页Chinese Journal of Nosocomiology

基　　金：高等学校博士学科点专项科研基金资助项目(200806310005)

摘　　要：目的对综合ICU患者多药耐药菌(MDR)感染情况进行分析,为MDR的预防和控制提供数据支持。方法取自2009年9月-2012年3月在医院综合ICU住院的298例患者送检标本1 965份进行分析,找出培养阳性的病原菌,筛选出MDR,并分析MDR的类型、感染部位分布等,所有数据采用SPSS 19.0进行分析。结果 1 965份标本共分离出病原菌746株,其中MDR 584株占78.3%,排前3位的MDR为鲍氏不动杆菌、肺炎克雷伯菌、铜绿假单胞菌,分别占32.0%、30.5%、12.8%;MDR感染部位分布以呼吸道、血液、泌尿道最多分别占48.5%、9.6%、3.9%;属于MDR医院感染的有306株,占52.4%。结论 MDR感染多由于医院感染而引起,因此应加强医院感染的管理,制定切实可行的管理制度,降低MDR感染的发生。OBJECTIVE To analyze multi-drug resistant （MDR） infections in the general ICU so as to provide data support for the prevention and control of MDR infections. METHODS Totally 1965 specimens from 298 patients hospitalized in general ICU from Sept. 2009 to Mar. 2012 were analyzed to identify the pathogens with positive cultivation, MDR strains were screened and the types and infected site distribution of MDR infection were ana- lyzed. All data were analyzed by SPSS 19.0. RESULTS Totally 724 strains of pathogens were isolated from 1965 specimens, including 392 MDR pathogens （78.3%）, the top three strains of MDR pathogens were Acinetobacter baurnannii （32.0 %）, Klebsiella pneumoniae （30.50%）, and Pseudomonas aeruginosa （ 12.8 %）. Infected sites were mainly respiratory tract （48.5%）, blood （9.6%）, and urinary tract （3.9%）. Totally 306 strains belonged to MDR strains for hospital infections, accounting for 52.4%. CONCLUSION MDR infection was mainly caused by hospital infections, so hospitals should strengthen the management of hospital infections and develop practical management system to reduce occurrence of MDR infections.

关 键 词：综合重症监护病房 多药耐药菌 医院感染 

分 类 号：R378[医药卫生—病原生物学]