C-反应蛋白检测在妇产科感染性疾病的诊断研究  

Study on the value of C-reactive protein in the diagnosis of infective diseases in obstetrics and gynecology

作　　者：周莉[1] 牛艳红[1] 冀会萍 

机构地区：[1]安丘市中医院门诊部,山东安丘262100 [2]青州市人民医院神经内科,山东青州262500

出　　处：《中华医院感染学杂志》2014年第15期3885-3886,3895,共3页Chinese Journal of Nosocomiology

基　　金：潍坊市科技局基金资助项目(潍科成鉴字[2010]192)

摘　　要：目的探讨C-反应蛋白(CRP)检测在妇产科感染性疾病的诊断价值研究,以便对妇科感染的早期诊断提供支持。方法选取医院2009年1月-2012年12月收治的妇产科感染患者60例,其中严重感染20例,局部感染40例,并对同期进行健康体检的60名作为对照研究;观察患者血清CRP浓度、红细胞沉降率(ESR)、白细胞计数(WBC)、中性粒细胞比值(N),并与正常组对照进行比较;观察各个指标的检测在妇产科感染性疾病中的敏感性,采用SPSS17.0软件进行统计分析。结果妇产科感染的患者血清中CRP、WBC、ESR以及中性粒细胞比值分别为(92.23±32.37)mg/L、(11.32±3.13)×109/L、(19.81±10.76)mm/h以及(72.31±10.12)%均高于正常组的(6.13±2.77)mg/L、(7.87±1.36)×109/L、(9.74±5.62)mm/h和(60.91±5.79)%;且CRP浓度在严重感染组(92.23±32.37)mg/L显著高于局部感染组(27.14±2.43)mg/L及正常对照组(6.13±2.77)mg/L,而在感染组CRP升高又较WBC、ESR、N等指标敏感。结论 CRP检测在妇产科感染性疾病的诊断和鉴别诊断中,具有敏感、快捷的特点,优于WBC、N,可作为妇产科感染诊断、病情监测、疗效评估和预后判断的敏感指标,具有很高的临床应用价值。OBJECTIVE To discuss the value of C-reactive protein in the diagnosis of infective diseases in gynecglogic infections. METHODS Totally 60 patients with obstetric and gynecological infections from Jan. 2009 to Dec. 2012 in our hospital were studied, of which 20 had severe infections, 40 had local infections. Another 60 healthy people were also enrolled as the control group. CRP concentration, erythrocyte sedimentation rate （ESR）, White blood cell count （WBC）, neutrophil ratio （N） in patients sera were observed and compared with the normal group. The sensitivity of each indicator in the diagnosis of obstetric and gynecological infections was observed and the results were statistically analyzed with SPSS 17. 0. RESULTS CRP, WBC, ESR and neutrophil ratios in the obstetric infected serum were （92. 23±32. 37） mg/L, （11. 32±3. 13）×10^9/L, （19. 81±10. 76） mm/h and （72.31±10.12） % and were higher than the normal group （6.13±2.77） mg/L, （7.87±1.36） × 10^9/L, （9.74 ±5.62） mm/h and （60. 91±5.79）%. And the CRP level in severe infection （92. 23±32.37） mg/L was significantly higher than local infection group （27. 14 ± 2. 43） mg/L and normal control group （6. 13 ±2. 77） mg/L, while in the infected group CRP was elevated and more sensitive than WBC, ESR, N and other indicators. CONCLUSION CRP testing in the diagnosis of obstetric and gynecological infections is sensitive and fast. It is better than the indicators of WBC and N, which can be used as the sensitive indicator in the diagnosis of obstetric and gynecological infections, disease monitoring, efficacy assessment and prognosis, with a high clinical value.

关 键 词：妇产科 C-反应蛋白 感染性疾病 

分 类 号：R446[医药卫生—诊断学]