复方丙酸氯倍他索软膏联合窄谱中波紫外线治疗原发性皮肤淀粉样变病30例临床观察  

Clobetasol Propionate Compound Ointment Plus NB-UVB Phototherapy in the Treatment of Primary Cutaneous Amyloidosis: A Clinical Observation in 30 Cases

作　　者：吴晓琦[1] 张荷香[1] 

机构地区：[1]江苏省原子医学研究所附属江苏省江原医院皮肤科,江苏无锡214063

出　　处：《中国皮肤性病学杂志》2014年第8期807-808,共2页The Chinese Journal of Dermatovenereology

摘　　要：目的探讨复方丙酸氯倍他索软膏联合窄谱中波紫外线治疗原发性皮肤淀粉样变病的临床疗效和安全性。方法将入选的60例原发性皮肤淀粉样变病患者随机分成两组,各30例。治疗组:患处外搽复方丙酸氯倍他索软膏,再予窄谱中波紫外线局部隔日照射1次,3次/周;对照组仅予窄谱中波紫外线局部照射治疗,方法同治疗组。两组患者的疗程均为4周。结果治疗结束后,治疗组有效率为83.33%,对照组为53.33%,差异有统计学意义(P<0.05)。治疗组有1例局部皮肤出现潮红、浸渍;对照组有1例出现轻微灼痛感觉。结论复方丙酸氯倍他索软膏联合窄谱中波紫外线治疗原发性皮肤淀粉样变病比单纯使用窄谱中波紫外线治疗的效果好。Objective To observe the clinical efficacy of clobetasol propionate compound ointment combined with NB- UVB phototherapy for primary cutaneous amyloidosis. Methods Sixty patients with primary cutaneous amy- loidosis were randomly divided into two groups. Treatment group ： thirty cases were treated by clobetasol propi- onate compound ointment combined with NB-UVB phototherapy three times weekly for 4 weeks. Control group ： thirty cases accepted NB-UVB phototherapy three times weekly for 4 weeks. Results The total effica- cy in the treatment group （83.33%） was signigicantly higher than that in the control group（53.33% ） （P 〈 0.05 ）. Conclusion Clobetasol propionate compound ointment combined with NB-UVB phototherapy is more effective than UVB alone for treatin~ orimarv cutaneous amyloidosis.

关 键 词：复方丙酸氯倍他索软膏 窄谱中波紫外线 淀粉样变病 临床观察 

分 类 号：R758.6[医药卫生—皮肤病学与性病学]