不同麻醉方式致人类免疫缺陷病毒感染患者麻醉并发症的临床研究  

Clinical studies of different anesthetic-induced anesthesia complications in patients with HIV infections

作　　者：张维维[1] 王耀岐[1] 贾树山[1] 

机构地区：[1]滨州医学院附属医院麻醉科,山东滨州256602

出　　处：《中华医院感染学杂志》2014年第16期4090-4092,共3页Chinese Journal of Nosocomiology

基　　金：山东省卫生厅重点基金资助项目(SW-2010B-039)

摘　　要：目的研究不同麻醉方式对人类免疫缺陷病毒(HIV)感染者麻醉并发症影响情况,提高该类患者的麻醉质量。方法选取2010年1月-2013年1月行手术治疗的HIV感染者90例,按照感染者手术麻醉方式不同分为全身麻醉组、局部麻醉组和腰硬联合麻醉组,各30例,比较3组不同时间段生命体征、手术切口、术后发生并发症等,所有数据采用SPSS 13.0分析。结果腰硬联合麻醉组术前CD4+T淋巴细胞计数(320.4±138.6)μl明显高于全身麻醉组(205.3±142.9)μl和局部麻醉组(196.2±142.4)μl;局部麻醉组麻醉时间(112.2±76.5)min明显低于全身麻醉组(178.2±124.8)min;全身麻醉组和腰硬联合麻醉组并发症发生率明显高于局部麻醉组,差异均有统计学意义(P<0.05)。结论 3种麻醉方式运用于HIV感染患者均具有相当的安全性,临床可根据患者情况以及手术类别进行选用。OBJECTIVE To study the situation of anesthetic complications by using different anesthetic on human immunodeficiency virus（HIV）-infected persons,so as to improve the quality of clinical anesthesia in these patients.METHODS A total of 90 cases of HIV infected patients received operation during Jan.2010 to Jan,2013 were selected,according to different anesthesia to infected patients,who were divided into groups,general anesthesia group,local anesthesia group and combined spinal-epidural anesthesia group,30 patients in each group,comparing three groups of different time periods vital signs,surgical incision,postoperative complications and so on.SPSS13.0 software was used for statistical analysis.RESULTS The CD4＋ T lymphocyte count for combined spinal-epidural anesthesia group before surgery was（320.4±138.6）μl which was significantly higher than the general anesthesia group（205.3±142.9）μl and local anesthesia group（196.2±142.4）μl,the difference was significant.Anesthesia time for local anesthesia was（112.2±76.5）min which was significantly lower than the general anesthesia group（178.2±124.8）min.Between general anesthesia and epidural anesthesia group,the incidence of complications was significantly higher than local anesthesia group（P0.05）.CONCLUSION Three different kinds of anesthesia were safe for HIV-infected patients,which can be selected according to the clinical condition of patients and surgical categories.

关 键 词：麻醉方式 人类免疫缺陷病毒 感染 并发症 影响 

分 类 号：R512.91[医药卫生—内科学]