TORCH感染与不良妊娠结局的关系研究  

Correlation between TORCH infections and adverse pregnancy outcomes

作　　者：牛艳红[1] 于周涛 冀会萍 

机构地区：[1]安丘市中医院妇产科,山东安丘262100 [2]青州市人民医院神经内科,山东青州262500

出　　处：《中华医院感染学杂志》2014年第16期4103-4104,4107,共3页Chinese Journal of Nosocomiology

基　　金：潍坊市科技局基金资助项目(潍科成鉴字[2010]192)

摘　　要：目的探讨TORCH感染与不良妊娠结局的关系,为优生优育提供试验依据。方法选取医院2012年1月-2013年1月进行产前检查的孕妇600例进行分析,对妊娠结局不良的53例孕妇与50名健康妇女对照比较,观察微生物感染阳性率,所有数据采用SPSS17.0分析。结果血清弓形虫IgM阳性2例、IgG阳性37例,阳性率分别为0.33%、6.17%;风疹病毒IgM阳性7例、IgG阳性501例,阳性率分别为1.17%、83.50%;巨细胞病毒IgM阳性4例、IgG阳性586例,阳性率为0.67%、97.67%;单纯疱疹病毒Ⅰ型IgM阳性8例、IgG阳性250例,阳性率为1.33%、41.67%;单纯疱疹病毒Ⅱ型IgM阳性7例、IgG阳性102例,阳性率为1.17%、17.00%;与健康组相比,TORCH-IgM阳性感染率显著升高,差异有统计学意义(P<0.05)。结论孕前进行TORCH筛查,防止孕前、孕期的TORCH感染,以便及时采取方法和措施,预防出生缺陷,提高人口素质,对优生优育意义重大。OBJECTIVE To investigate the relationship of TORCH infections and adverse pregnancy outcomes so as to provide experimental evidence for good birth for women.METHODS Totally 600 pregnant women in our hospital from Jan.2012 to Jan.2013 were studied.Fifty pregnant women with adverse pregnancy outcomes were compared with 50 healthy women and were observed for the positive rate of microorganism infections,all data were analyzed with SPSS 17.0.RESULTS There were 2cases of IgM positive,and 37 cases of IgG positive for toxoplasma,with the positive rate of 0.33% and 6.17%;7cases of IgM positive and 501 cases of IgG positive for rubella virus,with the positive rate of 1.17% and 83.50%;4cases of IgM positive and 25 cases of IgG positive for cytomegalovirus,with the positive rate of 0.67% and 97.67%;8cases of IgM positive and 250 cases of IgG positive for herpes simplex virus typeⅠ,with the positive rate of 1.33% and 41.67%;7cases of IgM positive and 102 cases of IgG positive for herpes simplex virus typeⅡ,with the positive rate of 1.17% and 17.00%.Compared with the healthy group,TORCH-IgM-positive infection rate was significantly increased（P0.05）.CONCLUSION TORCH screening before pregnancy is of great significance as it helps to prevent TORCH infections before pregnancy and during pregnancy and can be suggestive of timely methods and measures,thus to prevent birth defects and improve population quality.

关 键 词：孕妇 TORCH感染 不良妊娠 酶联免疫吸附试验 

分 类 号：R181.32[医药卫生—流行病学]