参花妇康胶囊中丹参醇提取工艺研究  

Extracting Technology of TanshinoneⅡ_A from Shenhua Fukang Capsule

作　　者：周健 宋岐 金向群[2] 

机构地区：[1]吉林辉南三和制药有限公司,吉林通化135100 [2]吉林大学药学院,吉林长春130021

出　　处：《中国药业》2014年第15期49-51,共3页China Pharmaceuticals

摘　　要：目的利用高效液相色谱法优化参花妇康胶囊中丹参醇提取工艺。方法以干膏率及干膏中含丹参酮ⅡA的量为指标,通过正交试验筛选最佳提取工艺。结果最佳工艺条件为乙醇浓度70%,溶剂量6倍,提取时间3 h,提取次数2次。结论醇提法可用于丹参中有效成分的提取。Objective To optimize the extraction process of tanshinoneⅡA from Shenhua Fukang Capsule by HPLC. Methods Taking the dry extract rate and the tanshinoneⅡA content as the indexes, the best technological conditions were screened by the orthogonal design. Results The optimum conditions were 6 times the amount of 70% alcohol, extracting for 2 times, each time for 3 h. Conclusion The alcohol extraction method can be used to extract the effective ingredients in Salviae miltiorrhiza Bunge.

关 键 词：丹参酮ⅡA 乙醇提取 正交试验 

分 类 号：R284.2[医药卫生—中药学] R286.0[医药卫生—中医学]