L-瓜氨酸的合成  

The synthesis of L-citrulline

作　　者：刘玲[1] 张昌生[1] 张玲[1] 郑友广[1] 刘毅[1] 

机构地区：[1]徐州医学院药学院,江苏徐州221004

出　　处：《中国医药工业杂志》2014年第8期717-718,共2页Chinese Journal of Pharmaceuticals

摘　　要：L-鸟氨酸盐酸盐经锌离子络合反应、氨基甲酰化反应得瓜氨酸锌,不经分离,直接以等量硫化钠脱锌得L-瓜氨酸,总收率为65%,纯度98.7%。L-Citmlline was synthesized from L-omithine monohydrochloride by chelation with ZnSO4·7H2O and carbamylation with urea to give citmlline zinc, followed by the removal of zinc ions by NazS without filtration with an overall yield of 65 % and purity of 98.7 %.

关 键 词：L-瓜氨酸 L-鸟氨酸 锌络合物 合成 

分 类 号：O623.736[理学—有机化学]