模拟移动床色谱拆分D-塔格糖和D-半乳糖的模拟研究  

Simulation Study on Separation of D-tagatose and D-galactose in Simulated Moving Bed

作　　者：苏齐[1] 李会[1] 査小玲 徐进[1] 

机构地区：[1]温州大学化学与材料工程学院,浙江温州325035

出　　处：《当代化工》2014年第7期1379-1381,1385,共4页Contemporary Chemical Industry

基　　金：浙江省科技计划项目;项目编号:2010R10043

摘　　要：模拟移动床色谱操作参数的模拟和优化对实际分离生产具有重要的指导意义。本文采用平衡扩散模型,对模拟移动床色谱分离D-塔格糖和D-半乳糖进行了模拟研究,根据三角形理论确定了其最佳操作参数,并考察了各区柱数配置、切换时间和分离区流量等变化对分离效果的影响,验证了模拟移动床操作参数的敏感性和模型建立的必要性。The simulation and optimization of simulated moving bed （SMB） operation parameters are significant for the practical application. In this paper, the equilibrium-dispersive mode was used to simulate the SMB process for the separation of D-tagatose and D-galactose. The optimal operating parameters were determined by the triangle theory. And effects of column distribution ,switching time and flow-rate in section Ⅱand Ⅲ on the separation efficiency were investigated.

关 键 词：模拟移动床色谱 D-塔格糖 D-半乳糖 分离模拟 

分 类 号：TQ028.9[化学工程]