爬沙虫提取液对小鼠生长发育及繁殖性能的影响  

Effects of Protohermes grandis Extract on Growth and Reproduction of Mice

作　　者：杨冬梅[1] 梁静[1] 廖鹏[1] 龙灿[1] 罗丽[1] 李俊年[1] 

机构地区：[1]吉首大学生物资源与环境科学学院

出　　处：《天然产物研究与开发》2014年第8期1290-1293,共4页Natural Product Research and Development

基　　金：国家自然科学基金项目(30570285);湖南省科技厅重点计划项目(2012NK2013);湖南省教育厅研究生创新基地项目(201103A);湖南省生态学重点学科建设项目(20130713)

摘　　要：为探讨爬沙虫提取液对小鼠生长发育及繁殖性能的影响,分别以含2.500%、1.250%、0.625%爬沙虫提取液的饲料及基础饲料喂养小鼠,结果表明爬沙虫提取液对小鼠生长发育无显著影响,可缩短F1雌鼠初次产仔时间、增加窝仔数、提高F1雌鼠子宫指数,提高F1雄鼠精子密度,增加F2断乳前成活率。因此,爬沙虫提取液可促进小鼠繁殖性能,且0.625%爬沙虫提取液对小鼠繁殖力的促进作用最明显,而2.500%爬沙虫提取液则对小鼠繁殖具有抑制作用。The aim of this study was to investigate the effects of Protohermes grand/s extract on the growth and reproduction of mice. Different concentrations （0. 625%, 1. 250% and 2. 500% ） of P. grandis extracts were investigated. The resuits showed that there were no significant effects of P. grandis extracts on the mice＇ s growth; The first littering time of P. grandis extract group was shorten; The litter size,ovary＇ s index and the survival rate of F2 before weaning and the sperm density of P. grandis extract group were increased significantly. This study demonstrated that P. grandis extracts can promote mice＇ s reproductive performance. In addltlon,mice＇ s reproduction was improved significantly by 0. 625% of P. grandis extract,while it was inhibited by 2. 500% of P. grandis extract.

关 键 词：爬沙虫 小鼠 体重 窝仔数 繁殖 精子 

分 类 号：R285.5[医药卫生—中药学]