活血化瘀方案对脑出血患者生活质量改善的影响  

Effect for Improving Living Quality of Intracerebral Hemorrhage with Blood-activating and Stasis-removing Therapy

作　　者：陈澈[1] 院立新 李净娅[2] 张根明[3] 

机构地区：[1]北京中医药大学第一临床医学院,北京100029 [2]北京中医药大学第三临床医学院,北京100029 [3]北京中医药大学东直门医院脑病科,北京100700

出　　处：《中国药物警戒》2014年第8期462-464,共3页Chinese Journal of Pharmacovigilance

基　　金：北京市科委科技计划重大项目"脑卒中两项中医关键治疗方案规范研究"(D101107049310003)

摘　　要：目的观察活血化瘀方案对脑出血患者生活质量改善的影响。方法 228例脑出血患者随机分为两组。对照组114例予内科基础治疗,试验组114例在此基础上予醒脑静注射液静脉滴注14天,辨证服用活血化瘀免煎颗粒21天,21天后口服脑血疏口服液至发病3个月。观察两组基于中风患者报告的临床结局(PRO量表)评分变化情况。结果试验组在入组第21天及3个月时PRO量表的生理功能、心理精神状态、社会关系和治疗满意度等指标总分均低于对照组(P<0.05)。且各单项指标分值在一些时点亦低于对照组(P<0.05)。结论活血化瘀方案可改善脑出血患者在发病后一定时期内的生活质量,对于提高脑出血的临床疗效有一定意义。Objective To observe the effect for improving living quality ofintracerebral hemorrhage with blood-activating and stasis-removing therapy. Methods A total of 228 cases with cerebral hemorrhage were randomly divided into the treatment group （n=114） and the control group （n=114）. The control group was treated with the basic treatment of internal medicine. On the basis of it, the treatment group received intravenous infusion with Xingnaojing injection for 2 weeks and was given TCM granules for 21 days dynamically and dialectically. After these, the treatment group was asked to drink Naoxueshu oral liquid until the 3rd month of incidence. The clinical outcome assessment of pa- tient reported outcomes （PRO） scores were observed in two groups. Results Compared with the first day, the treat- ment group PRO scores were superior to control group in 21th day and 3rd month after entering the group （P 〈 0.05）. And the single index in some time was also lower than the control group （P〈0.05）. Conclusion lntracere- bral hemorrhage with blood-activating and stasis-removing therapy had an effective result in improving living quali- ty in a certain period of time. It is good to improve the clinical efficacy.

关 键 词：脑出血 活血化瘀 生活质量 临床观察 

分 类 号：R971[医药卫生—药品] R243[医药卫生—药学]