通督益颈汤对气滞血瘀型椎动脉型颈椎病血流动力学的影响研究  

Research of Tongduyijing decoction on hemodynamics of vertebral artery type cervical spondylosis with qi stagnation and blood stasis type

作　　者：王玉才 张小健 毛燕 张福磊 李长聪 梁慧 

机构地区：[1]北京市顺义区中医医院脑病一病区,北京顺义101300 [2]北京市顺义区社区卫生服务中心,北京顺义101300

出　　处：《河北中医》2014年第9期1297-1299,1302,共4页Hebei Journal of Traditional Chinese Medicine

基　　金：北京市中医药科技项目(编号:JJ2009-40)

摘　　要：目的通督益颈汤对气滞血瘀型椎动脉型颈椎病(CSA)血流动力学的影响。方法对195例气滞血瘀型CSA患者随机分为2组。2组均予以对症基础治疗,对照组92例予盐酸氟桂利嗪胶囊口服治疗,治疗组105例予通督益颈汤治疗。2组均治疗21 d后,观察比较2组证候量化积分变化,经颅多普勒检测双侧椎动脉及基底动脉血管搏动指数(PI)及脑血管阻力指数(RI)的变化,颈部彩超检测双侧椎动脉内径及血流峰值变化。结果 2组治疗后中医证候量化积分均有明显减少(P<0.05),且治疗组改善优于对照组(P<0.05);对照组治疗前后双侧椎动脉及基底动脉PI和RI无明显变化(P>0.05),治疗组治疗后均明显降低(P<0.05),与对照组比较差异有统计学意义(P<0.05);2组治疗后双侧椎动脉内径均无明显变化(P>0.05);对照组治疗前后双侧椎动脉血流峰值无明显变化(P>0.05),治疗组治疗后均明显增加(P<0.05),与对照组比较差异有统计学意义(P<0.05)。结论通督益颈汤治疗气滞血瘀型CSA可明显改善患者中医证候表现,纠正椎-基底动脉血液动力学紊乱,临床疗效显著,值得进一步应用推广。Objective To explore the effect of Tongduyijing decoction on hemodynamics of vertebral artery type cervical spondylosis with qi stagnation and blood stasis type. Methods 195 vertebral artery type cervical spon- dylosis patients with qi stagnation and blood stasis type were randomly divided into two groups. Two groups are to suit the foundation treatment. 92 patients in control group were treated by flunarizine hydrochloride. 105 cases in treatment group were treated by Tongduyijing decoction. Syndrome quantitative integral change, transcranial Doppler bilateral vertebral artery and basilar artery pulsatility index （PI）and cerebral vascular resistance index （RI）changes, neck ul- trasound to detect bilateral vertebral artery diameter and blood flow changes in peak were observed after 21 days of treatment. Results Traditional Chinese medicine syndrome quantitative integral after treatment were obviously de-creased in two groups （ P 〈 0.05 ）. The improvement in the treatment group was more than that in the control group （ P 〈 0.05 ）. There was no difference between before and after treatment on bilateral vertebral artery and basilar artery PI and RI in control group （ P 〉 0.05 ）. Bilateral vertebral artery and basilar artery PI and RI after treatment were sig-nificantly decreased in treatment group （ P 〈 0.05 ）. There was significant difference between two groups （ P 〈 0.05 ）. There was no difference between before and after treatment on bilateral vertebral artery blood flow peak in control group （ P 〉 0.05 ）. Bilateral vertebral artery blood flow peak after treatment were significantly increased in treatment group （ P 〈 0.05 ）. There was significant difference between two groups （ P 〈 0.05 ）. Conclusion Tongduyijing decoction can obviously improve the traditional Chinese medicine syndrome in cervical spondylosis patients with qi stagnation and blood stasis type, correct vertebral-basilar artery hemodynamics disorders, clinical curative effect is distinct, is wo

关 键 词：颈椎病 椎底动脉供血不足 气滞血瘀 中药疗法 

分 类 号：R287[医药卫生—中药学]