2005—2009年四川大学华西医院化妆品不良反应回顾性分析  

Retrospective analysis of cosmetic adverse reaction during 5 years

作　　者：谢小琴[1] 韩毅[1] 周成霞[1] 杨利蓉[1] 余瑶[1] 周慧[1] 孟慧敏[1] 蒋献[1] 李利[1] 

机构地区：[1]四川大学华西医院皮肤性病科,成都610041

出　　处：《实用皮肤病学杂志》2014年第4期270-272,共3页Journal of Practical Dermatology

摘　　要：目的探讨化妆品引起皮肤各种不良反应的状况及远期影响。方法对四川大学华西医院2005—2009年门诊疑为化妆品不良反应的487例患者进行回顾性临床分析,并对接诊后观察时间>6个月的患者进行随访。结果 487例患者以中青年女性居多,临床表现主要为化妆品接触性皮炎(65.3%),化妆品色素异常性皮肤病(10.9%),毛发损害(2.67%),化妆品痤疮(2.5%)。对281例患者行可疑化妆品斑贴试验,73例阳性。对169例进行了随访,87例(51.48%)经过治疗而痊愈,但是仍有近1/4患者症状反复出现,难以痊愈。结论选择化妆品应谨慎,相关卫生行政部门应重视化妆品的安全性监督和管理,各级临床医生对化妆品不良反应及时进行处理,减少并发症。Objective To evaluate adverse reactions and long-term effects caused by cosmetics. Methods A retrospective clinical analysis was carried out on total 487 outpatients suspected to be with cosmetics adverse reactions from 2005 to 2009. The patients with the observation time over six months were followed up. Results Young and middle-aged women were the majority of the patients, and the main clinical manifestations of the adverse reactions were cosmetic contact dermatitis, cosmetic pigment abnormal skin disease, hair damage and cosmetic acne, accounting for 65.3%, 10.9%, 2.67%, 2.5%, respectively. The suspected cosmetic patch tests were given to 281 patients, 73 cases presented positive result. For the 169 patients followed up, 87 patients（51.48%）were cured by treatment, while nearly 25% patients were difficult to cure, symptoms appeared repeatedly. Conclusions Cosmetics should be choosed carefully. The health administrative department should pay more attention to cosmetics safety supervision and management, and all clinicians should process cosmetics adverse reactions in time, so as to reduce the complications.

关 键 词：化妆品 不良反应 皮肤 随访 

分 类 号：R751[医药卫生—皮肤病学与性病学]