2型糖尿病伴肥胖患者胃旁路术后生活质量的改善  

Laparoscopic Roux-en-Y gastric bypass surgery improves quality of life for overweight type 2 diabetes mellitus patients

作　　者：李昆[1] 韩晓东[1] 狄建忠[1] 张弘玮[1] 周玉龙[1] 杜贻豹[1] 张频[1] 

机构地区：[1]上海交通大学附属第六人民医院普外科,200233

出　　处：《中华普通外科杂志》2014年第7期517-519,共3页Chinese Journal of General Surgery

摘　　要：目的 探讨腹腔镜下Roux-en-Y胃旁路术对2型糖尿病伴肥胖患者生活质量的影响.方法 以46例2型糖尿病伴肥胖患者作为研究对象,利用《SF-36量表》评估患者腹腔镜下Roux-en-Y胃旁路术术前、术后6个月和术后12个月生活质量的变化.结果 本组46例2型糖尿病伴肥胖患者的生理健康术前得分与平均值相比差异有统计学意义（P＜0.01）,术后6个月和术后12个月与术前相比均有明显改善（P＜0.01）.心理健康术前得分与平均值相比差异无统计学意义,术后6个月和术后12个月与术前相比有明显改善（P＜0.01）.生理机能、生理职能和情感职能三个维度：术后6个月（78 ±8、76±17、70 ±23）和术后12个月（85 ±7、82±18、77±18）比术前（68±13、58±21、50±22）明显改善（P＜0.0l）,并在术后12个月与平均值相比（85、81、82）差异无统计学意义.躯体疼痛、一般健康状况和社会功能三个维度：术后6个月（76±12、75 ±6、75±13）和术后12个月（82±9、79±6、94±9）比术前（66±14、55 ±12、63±15）明显改善（P＜0.01）.精神健康维度术前与平均水平相比差异无统计学意义,术后6个月和术后12个月与术前相比差异无统计学意义. 结论 2型糖尿病伴肥胖患者在胃旁路术后生理及心理健康水平有明显改善.Objective To investigate the change in quality of life （QoL） following laparoscopic Roux-en-Y gastric bypass （LRYGB） for T2DM with obesity.Methods A total of 46 overweight T2DM cases （mean baseline BMI （32.7 ± 3.9） kg/m2） undergoing LRYGB were followed by QoL questionnaires （SF-36） before and after 6 and 12 months.Results The preoperative physical QoL scales （physical component summary,PCS） was significantly different from the general population（GP） scales （P ＜ 0.01）,and the improvement in QoL was significant at 6 months postoperative and continued to consistently increase up to 12 months （P ＜ 0.01）.For mental component summary （MCS）,the preoperative scales was not significantly different from the GP scales,however,the 6 and 12 postoperative scales improved significantly （P ＜0.01）.As for physical function,role physical,role emotion,the 6 （78 ± 8,76 ± 17,70 ± 23） and 12 months＇ （85 ± 7,82 ± 18,77 ± 18） postoperative scales were markedly higher than those in the preoperative controls （P ＜ 0.01）,and there were no differences between the 12 month＇s postoperative scales and GP scales.The preoperative bodily pain,general health and social function （66 ± 14,55 ± 12,63 ±15） was different when compared with （76 ± 12,75 ±6,75 ± 13） at 6 months and （82 ±9,79 ±6,94 ±9） at 12 months （P ＜0.01）.The preopertive mental health （71 ± 12） was not significantly different from GP scales,nor there were significant difference when compared with （71 ± 10） at 6 months and （73 ±8） at 12 months.Conclusions There were improvements in physical and mental QoL in T2DM patients with obesity after LRYGB.

关 键 词：糖尿病 2型 肥胖症 病态 生活质量 胃旁路术 

分 类 号：R587.1[医药卫生—内分泌] R589.2[医药卫生—内科学]