宫颈原发性粒细胞肉瘤:病例报告并文献复习  

Primary Granulocytic Sarcoma of Cervix:A Case Report and Review of the Literature

作　　者：王颖[1] 周怡[1] 罗琳[1] 刘明辉[1] 左学兰[1] 

机构地区：[1]武汉大学中南医院血液内科,湖北武汉430071

出　　处：《武汉大学学报（医学版）》2014年第4期628-631,共4页Medical Journal of Wuhan University

摘　　要：目的:提高对原发性宫颈粒细胞肉瘤(PGSC)诊断的认识,提出治疗的新思路。方法:报道我院确诊的1例PGSC,搜集近10年国内外报道的PGSC病例进行临床和病理分析。结果:13例PGSC以阴道不规则流血为主要临床表现,需免疫组化确诊,治疗上多采用联合化疗。结论:免疫组化对PGSC早期诊断极为重要,全身强烈化疗可延长生存期,及早鞘内注射可预防中枢神经系统白血病。Objective： To study the diagnosis of primary granulocytic sarcoma of the cervix （PGSC） and put forward the new treatment of the disease. Methods： A case of PGSC was reported and the related literatures of PGCS reported in recent 10 years were reviewed. Results： All the 13 cases presented clinically with vaginal irregular bleeding, the diagnosis was based on the immunohistochemistry, and combination chemotherapy is the main treatment. Conclusion： Immunohistoehem- istry is extremely important for the diagnosis of PGSC, and the intensive chemotherapy is associated with longer survival. To prevent the leukemia of CNS, intrathecal injection as soon as possible is necessary.

关 键 词：粒细胞肉瘤 宫颈 原发性 治疗 

分 类 号：R557.3[医药卫生—血液循环系统疾病]