320排CT首过灌注成像鉴别良恶性肺结节初探  

Preliminary Study of Differentiating Benign and Malignant Pulmonary Nodules by 320-Slice CT with First-pass Perfusion Imaging (CT-PWI)

作　　者：丁汉军[1] 杨蕊梦[1] 黄云海[1] 崔嵩[1] 曹丽妃[1] 

机构地区：[1]广州医学院附属广州市第一人民医院放射科,广东广州510180

出　　处：《中国CT和MRI杂志》2014年第4期16-17,44,共3页Chinese Journal of CT and MRI

基　　金：2011年广东省第三批科技计划项目(粤科规划字[2011]97号-序号5)

摘　　要：目的探讨320排CT首过灌注成像鉴别良恶性肺结节的临床实用性。方法灌注成功并明确诊断的肺结节51例,包括12例肺炎性结节,5例肺良性结节,34例肺恶性结节,所有病例均进行320排CT肺部动态容积扫描,利用灌注软件获取肺结节兴趣区的灌注参数值,并进行统计学分析。结果通过肺结节灌注参数伪彩图获取病灶实质部分的肺动脉灌注量(PAP)、支气管动脉灌注量(BAP)、肺动脉灌注指数(PAPI)等参数值,肺炎性结节、肺良性结节、肺恶性结节三组的各项灌注参数均有显著性差异。结论 320排CT首过灌注成像对良恶性肺结节的鉴别诊断有优势,具有临床实用性和优越性。Objective To explore the clinical application of 320-slice CT first-passperfusion imaging （CT-PWI） in differentiating benign and malignant pulmonary nodules. Methods 51 patients were diagnosed as pulmonary nodules,including inflammation （n=12）, benign （n=5） and malignant（n=34）nodules. All the cases were performed thoracic dynamic volume CT examinations by 320-slice CT scanner. Perfusion parameters were acquired by perfusion software, and were statistically analyzed. Results Perfusion parameters such as pulmonary artery perfusion（PAP）, bronchial artery perfusion（BAP）, pulmonary artery perfusion index（PAPI） were acquired through pseudocolor maps. There were significant differences in the perfusion parameters among inflammatory, benign and malignant nodules. Conclusion Using 320-slice CT first-pass perfusion imaging（CT-PWI）, it has advantages in differentiating benign and malignant pulmonary nodules, which possess practicability and superiority in clinic.

关 键 词：体层摄影术 X线计算机 肺结节 灌注成像 

分 类 号：R445.3[医药卫生—影像医学与核医学] R734.2[医药卫生—诊断学]