感染旋毛虫小鼠心肌能量代谢变化的检测  

Research on myocardial fatty acid metabolism in mice infected with Trichinella spiralis

作　　者：许圆圆[1] 李巍[2] 韩彩霞[2] 路义鑫[2] 李兴超[1] 宋铭忻[2] 

机构地区：[1]哈尔滨医科大学,黑龙江哈尔滨150086 [2]东北农业大学,黑龙江哈尔滨150030

出　　处：《中国兽医杂志》2014年第6期25-26,29,共3页Chinese Journal of Veterinary Medicine

基　　金："十一五"国家科技支撑计划重大项目(2010BAD04B01)

摘　　要：本试验旨在对感染旋毛虫后小鼠心肌能量代谢变化进行研究。将小鼠接种旋毛虫1 000条/只后,分别检测小鼠心肌血管紧张素Ⅱ（AngⅡ）、过氧化物酶体增殖物激活受体（PPARs）和小鼠组织胰岛素。结果显示,旋毛虫感染小鼠后,AngII、PPARα及胰岛素的含量检测结果均呈现相似趋势,至19~24 d出现峰值,随后下降。试验结果为旋毛虫病的早期诊断、治疗提供基础数据。The experiment was conducted to study myocardial fatty acid metabolism in mice infected with Trichinella spiralis（T.spiralis）.Each Mouse was infected with 1000 of T.spiralis and peroxisome proliferator-activated receptor（PPAR） and angiotensinⅡ（AngⅡ） and insulin were detected.The results showed that the content of PPAR,AngⅡ and insulin reached the peak value from 19 to 24 days post infection with T.spiralis.The results provided the basic data for early diagnosis and treat of Trichinosis.

关 键 词：旋毛虫 心肌脂肪酸 代谢 

分 类 号：R383.15[医药卫生—医学寄生虫学]