鸡白痢沙门菌对四环素类药物耐药性和耐药基因调查分析  

Investigation of Resistance to Tetracycline and Distribution of Tetracycline Resistance Genes of Pullorum Salmonella

作　　者：宁家宝 梁梓森[1] 陈建红[2] 张济培[2] 涂玉蓉[1] 司兴奎[2] 牛森[2] 

机构地区：[1]华南农业大学兽医学院,广东广州510642 [2]佛山科学技术学院动物医学系,广东佛山528231

出　　处：《中国兽医杂志》2014年第7期39-41,共3页Chinese Journal of Veterinary Medicine

摘　　要：检测分析珠三角地区69株鸡白痢沙门菌对四环素的耐药性及5种四环素耐药基因[tet(A)、tet(B)、tet(C)、tet(M)和tet(X)]在分离株中的分布情况。结果显示,43株(62.7%)鸡白痢沙门菌分离株对四环素产生耐药性,耐药基因tet(A)的检出率为75.4%,未能检测到耐药基因tet(B)、tet(C)、tet(M)和tet(X),表明鸡白痢沙门菌对四环素的耐药机制以tet(A)基因介导的主动外排为主。The study aimed to; investigate the prevailing of tetracycline resistance and the distribution of tetracycline resistance genes tet （ A ） , Let （ B ） , tet （ C ） , tet （M） , and tet （ X ） in 69 Salmonella pullorum isolated from Pearl River Delta region. The results showed that 62.7% of the 69 isolates （43/69） were found to be resistant to tetracycline, and the detection rate of resistance gene tet （A） was 75.4%.However, tetB, tetC, tetM, and tetX genes were not detected, indicating that active efflux mediated by tet （A）gene is the primary mechanism of resistance to tetracycline in Salmonella pullorum.

关 键 词：鸡白痢沙门菌 四环素 耐药性 耐药基因 

分 类 号：S852.612[农业科学—基础兽医学]