母猪饲粮中添加精氨酸对仔猪肠道免疫细胞数量的影响  

Effects of Sow Diet Supplemented with Arginine on the Number of Intestinal Immunological Cells of Piglets

作　　者：寇涛[1] 吕佳琪[1] 李伟[1] 王恬[1] 

机构地区：[1]南京农业大学动物科技学院,南京210095

出　　处：《动物营养学报》2014年第8期2077-2084,共8页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：江苏高校优势学科发展计划项目

摘　　要：本试验旨在研究母猪饲粮中添加精氨酸（ Arg）对子宫内发育迟缓（ IUGR）仔猪肠道免疫细胞数量的影响。试验选择20头妊娠30 d 的母猪（长白×大白），随机分为2组（每组10头），分别饲喂基础饲粮和添加1％ Arg的基础饲粮至母猪生产。从饲喂基础饲粮的母猪所产的仔猪中选8头正常初生重母猪和8头 IUGR 母猪，分别为对照组和 IUGR 组；从饲喂添加1％Arg的基础饲粮的母猪所产仔猪中选择8头IUGR母猪，为Arg＋IUGR组，各组仔猪随母猪哺乳。于仔猪7和21日龄，每组随机选取4头仔猪屠宰，检测空肠及回肠黏膜免疫细胞数量。结果表明：Arg＋IUGR组仔猪8～21日龄及1～21日龄平均日增重高于IUGR组（ P＞0．05）；IUGR组仔猪7日龄小肠杯状细胞数量和21日龄回肠杯状细胞数量均显著低于对照组（ P＜0．05），Arg＋IUGR组仔猪7日龄空肠肥大细胞和回肠杯状细胞数量极显著高于 IUGR组（ P＜0．01），回肠肥大细胞和空肠杯状细胞数量也有所提高（ P＞0．05）；Arg＋IUGR组仔猪21日龄空肠肥大细胞和杯状细胞数量及回肠杯状细胞数量均显著高于IUGR组（ P＜0．05）。综上所述，母猪饲粮中添加Arg可提高IUGR仔猪平均日增重，增加后代IUGR仔猪肠道免疫细胞数量，增强仔猪肠道免疫力。This study was conducted to study the effects of sow diet supplemented with arginine（ Arg）on the number of intestinal mucosal immune cells of offspring piglets. On day 30 of gestation,twenty pregnant sows （Landrace×White）were randomly divided into 2 groups（10 pregnant sows per group）,receiving a basal diet and the basal diet supplemented with 1% Arg,respectively. Eight neonatal piglets with a normal birth weight （ control group）and 8 piglets with intrauterine growth retardation（ IUGR group）chosen from the sows fed the basal diet,respectively,and 8 IUGR piglets（ Arg＋IUGR group）chosen from the sows fed the basal diet sup-plemented with 1% Arg. Four piglets of each group were slaughtered to determine the number of immune cells in jejunum and ileum mucosae at 7 and 21 days of age. The results showed that compared with IUGR group, the average daily gain of piglets in Arg＋IUGR group was increased at 8 to 21 days of age and 1 to 21 days of age（ P〉0.05）. Compared with IUGR group,the number of mast cells in jejunum and goblet cells in ileum of piglets in Arg＋IUGR group were significantly increased at 7 days of age（ P〈0.01）,and the number of mast cells in ileum and goblet cells in jejunum were increased（ P〉0.05）. At 21 days of age,the number of mast cells and goblet cells in jejunum were significantly increased（ P〈0.05）,as well as the number of goblet cells in ileum（ P〈0.05）. The results indicate that the pregnant sow diet supplemented with Arg can increase the av-erage daily gain and the number of immune cells in intestinal mucosa of IUGR piglets,and enhance intestinal immunity of offspring.

关 键 词：精氨酸 IUGR仔猪 母体效应 小肠 肥大细胞 杯状细胞 

分 类 号：S828[农业科学—畜牧学]