A green and efficient access to aryl nitriles via an electrochemical anodic oxidation  

作　　者：Jia-Qian Ye Zhen-Lei Zhang Zheng-Gen Zha Zhi-Yong Wang 

机构地区：[1]Hefei National Laboratory for Physical Sciences at Microscale, CAS Key Laboratory of Soft Matter Chemistry & Collaborative Innovation Center of Suzhou Nano Science and Technology, University of Science and Technology of China

出　　处：《Chinese Chemical Letters》2014年第8期1112-1114,共3页中国化学快报（英文版）

基　　金：financially supported by the National Natural Science Foundation of China (Nos. 2127222, 91213303, 21172205, J1030412)

摘　　要：The nitrile functionality is a key building block in synthetic chemistry, and has wide applications in pharmaceuticals. However, traditional methodologies for the synthesis of nitriles are limited to harsh reaction conditions. Herein, we report a new and efficient access to aryl nitriles by an electrochemical synthesis. Compared with the conventional synthetic methods, this electrochemical synthesis is more environmentally friendly and easier to handle.The nitrile functionality is a key building block in synthetic chemistry, and has wide applications in pharmaceuticals. However, traditional methodologies for the synthesis of nitriles are limited to harsh reaction conditions. Herein, we report a new and efficient access to aryl nitriles by an electrochemical synthesis. Compared with the conventional synthetic methods, this electrochemical synthesis is more environmentally friendly and easier to handle.

关 键 词：Eletrochemistry Anodic oxidation Aryl nitrile 

分 类 号：O625.67[理学—有机化学] O641.4[理学—化学]