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机构地区:[1]Department of Cardiology, Boston Children's Hospital, Boston, MA 02115, USA [2]Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA
出 处:《Cell Research》2014年第7期777-778,共2页细胞研究(英文版)
摘 要:Regenerative medicine for cardiovascular disease requires effective approaches for therapeutic revascularization. In a recent paper in Cell Research, Sahara et al. establish a new role for Notch signaling to promote endothelial progenitor differentiation, and develop a protocol based on Notch inhibition in endothelial progenitors to markedly enhance the yield and purity of functional endothelial cells differentiated from embryonic stem cells.
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