慢性淋巴细胞性甲状腺炎与甲状腺恶性肿瘤的临床相关性  

Clinical correlational research between CLT and malignant tumours of the thyroid

作　　者：张懿[1] 邓福生[1] 刘政溶[1] 韦后清[1] 王锡宏[1] 马小鹏[1] 陈浩[1] 

机构地区：[1]安徽医科大学附属省立医院普通外科,合肥230001

出　　处：《安徽医科大学学报》2014年第8期1145-1147,共3页Acta Universitatis Medicinalis Anhui

基　　金：安徽省卫生厅科研基金资助项目(编号:13ZC007)

摘　　要：目的探讨慢性淋巴细胞性甲状腺炎(CLT)与甲状腺恶性肿瘤之间的临床相关性。方法回顾性分析647例进行手术的甲状腺患者,研究CLT与甲状腺恶性肿瘤的关系,分析44例合并有CLT的甲状腺恶性肿瘤患者的临床资料。结果 CLT患者中甲状腺恶性肿瘤发病率为40.7%,非CLT患者中发病率为18.7%,两者比较差异有统计学意义(P<0.05)。甲状腺恶性肿瘤中CLT和非CLT患者TNM分期无明显差异。结论 CLT合并甲状腺癌的比例较高,当B超提示甲状腺肿块有微小钙化、边界不清或颈部淋巴结肿大时,应积极诊治并谨慎评估恶性的可能性。CLT对甲状腺恶性肿瘤分期无影响。Objective To discuss the clinical correlation between CLT and malignant tumours of the thyroid.Methods In this study,patients operated on for thyroid diseases in Anhui Provincial Hospital in 2012 were investigated retrospectively.Patients diagnosed as having CLT were investigated for any concurrent malignant neoplasm.44 patients in whom CLT and thyroid malignancy were coexisting were recruited in the study.Results In our study,the rate of malignancy against the background of CLT was 40.7％,while the rate in the groups without CLT was 18.7％,with a statistically significant difference between the groups （P ＜ 0.05）.There was no statistical difference in TNM classification between the groups with and without CLT.Conclusion The rate of throiditis coexistent with thyroid carcinoma is higher.The patients with microcalcifications,irrgular border or cervical lymphadenectasis in preoperative sonogram should be evaluated more carefully in terms of malignancy.CLT has no effect on clinical TNM classification of malignant tumours of thyroid.

关 键 词：甲状腺炎 甲状腺恶性肿瘤 相关性 

分 类 号：R581.4[医药卫生—内分泌] R736.1[医药卫生—内科学]