急性心肌梗死PCI术后微泵注射替罗非班的疗效观察和护理  

Effect observation and care of acute myocardial infarction after PCI by micropump tirofiban injection

作　　者：余碧清[1] 查海燕[1] 

机构地区：[1]深圳市罗湖区人民医院心血管内科,广东深圳518001

出　　处：《中国医药科学》2014年第14期163-165,共3页China Medicine And Pharmacy

摘　　要：目的：探讨急性心肌梗死PCI术后微泵注射替罗非班的的临床疗效及护理的临床效果。方法收集2013年1月～2014年1月来我院就诊并采用PCI治疗的118例急性心肌梗死患者，将患者按照随机数字表法分为观察组59例，微量泵持续泵入替罗非班，对照组59例，微量泵持续泵入肝素，并实施临床护理措施比较两组给药前后心电图改善情况及不良事件发生情况。结果观察组及对照组用药48h后ST段值及缺血导联数均低于用药前，差异有统计学意义（P＜0.05），观察组用药后48h改善程度明显大于对照组，差异有统计学意义（P＜0.05）。观察组不良事件总发生率为8.47%，对照组为13.56%，两组不良事件总发生率差异无统计学意义（P＞0.05）。结论急性心肌梗死患者PCI术后微泵注射替罗非班明显改善患者心电图情况，对相关血管的心肌血液供应有明显的改善，对不良事件总发生率影响较小。Objective To investigate the clinical efficacy and care of acute myocardial infarction after PCI by micropump tirofiban injection. Methods 118 cases of acute myocardial infarction with PCI were selected from January 2013 to January 2014 in our hospital and randomly divided into 59 cases of observation group with micropump tirofiban continuous injection and 59 patients of control group with micropump heparin continuous injection,and implemented clinical care measures,and compared in ECG improvement and occurrence of adverse events before and after administration. Results The ST value and ischemia lead number after 48h of administration in observation group and control group were lower than before administration,the difference was statistically significant（P〈0.05）,ECG improvement degree after 48h of administration in observation group was significantly greater than that in the control group,the difference was statistically significance（P〈0.05）.The overall incidence of adverse events in observation group was 8.47%,that in the control group was 13.56%,the overall incidence of adverse events in both groups showed no significant difference（P 〉 0.05）. Conclusion The patients with acute myocardial infarction after PCI by micropump tirofiban injection significantly improve patient＇s electrocardiogram,the myocardial blood supply of the relevant vessels,has smaller effect on the overall incidence of adverse events.

关 键 词：急性心肌梗死 PCI 替罗非班 微泵 护理 

分 类 号：R473.5[医药卫生—护理学]