2012年浙江省台州地区疑似预防接种异常反应监测分析  

Surveillance for adverse event following immunization in Taizhou,Zhejiang,2012

作　　者：王连华[1] 陈怡平[1] 

机构地区：[1]台州市疾病预防控制中心,浙江台州318000

出　　处：《疾病监测》2014年第7期552-555,共4页Disease Surveillance

摘　　要：目的 分析浙江省台州地区疑似预防接种异常反应（adverse event following immunization，AEFI）发生特征，为提高疫苗预防接种服务质量提供依据。 方法 通过全国AEFI信息管理系统收集2012年台州地区发生的AEFI个案数据，用描述性流行病学方法进行分析。 结果 台州地区2012年共报告173例AEFI，所辖9个县（市、区）均有AEFI报告，县级覆盖率100%，48 h内报告率98.27%，报告后48 h内调查率100%。1岁及以下的儿童共报告112例AEFI病例，占64.74%；一般反应136例，占78.6%；异常反应26例，占15.0%；偶合反应10例，占5.8%；心因性反应1例，占0.58%。AEFI发生时间主要集中在接种后0-1 d，共报告157例，占90.75%；报告病例中治愈或好转共172例，占99.4%。 结论 台州地区AEFI报告及时率、调查及时率和AEFI监测敏感性均较高，免疫规划疫苗接种的安全性和服务质量均良好。Objective To understand the incidence pattern of adverse event following immunization （AEFI） and identify the related factors, and provide evidence for the improvement of the quality of vaccination services. Methods The incidence data of AEFI in Taizhou during 2012 were collected through national AEFI information management system and the descriptive epidemiological analysis was conducted. Results Totally 173 AEFI cases were reported in 2012 through AEFI information management system in Taizhou. AEFI were reported in all 9 counties, the overall reporting rate within 48h was 98. 27% and the investigating rate within 48 hours after reporting was 100%. Among the 173 cases, 112 were children less than 1 years old, accounting for 64. 74% ; Among the AEFI cases, 136 were mild reactions, 26 were abnormal reaction, 10 were joint reactions and 1 was psychogenic reaction, accounting for 78.6%, 15.0%, 5.8% and 0. 58% respectively. AEFI occurred within 1 day after vaccination in 157 people, accounting for 90. 75% ; Among the AEFI cases, 172 were cured, accounting for 99. 4%. Condusion AEFI surveillance system in Taizhou worked well. The reporting rate, investigating rate within 48 hours and the sensitivity of AEFI surveillance were at high levels. The vaccination safety and service quality were ensured.

关 键 词：疑似预防接种异常反应 监测 报告率 

分 类 号：R186[医药卫生—流行病学]