抗菌药物在细胞内分布的文献计量分析  

Literature measurement analysis of intracellular antimicrobial agents in the permeability distribution

作　　者：白楠[1] 梅和坤[1] 唐铭婧[1] 曹江[1] 江学维[1] 张明[1] 王瑾[1] 王睿[1] 

机构地区：[1]解放军总医院药品保障中心临床药理研究室,北京100853

出　　处：《中国临床药理学杂志》2014年第8期733-735,共3页The Chinese Journal of Clinical Pharmacology

基　　金：国家科技部十二五国家重大科技专项基金资助项目(2012ZX09303004-002)

摘　　要：目的用文献计量学方法分析抗菌药物在细胞内分布的研究进展,为选择杀死胞内寄存病原体的抗菌药物研究提供参考。方法检索自建库到2013-08Pubmed,Embase,SCI,及CNKI数据库公开发表的文献,用EndNote软件进行整理,对其发表年份、作者、研究机构、被引频次及论著的研究内容进行计量分析。结果共纳入外文文献901篇,中文文献14篇。文献类型以论著(548篇)为主,其次为综述(175篇);被引频次最高为131次;多数文献为抗菌药物治疗感染及胞内细菌耐药机制研究方面的文章。结论抗菌药物在细胞内分布的研究日益受到全球的广泛关注,研究内容愈加深入。Objective To analyze the recent progress on intracellular an-timicrobial agents distribution over the past 50 years with bibliometric ap-proach , and to provide reference for study on choosing of antimicrobial a-gents to kill intracellular hosting pathogens.Methods Literatures were searched in Pubmed , Embase , Science Citation Index , and CNKI data-bases from beginning to August 2013.EndNote 7.0 was used to sort these articles and the bibliometric analysis was carried out in respect of published years , author , research institutions , cited frequency , and re-search contents etc.Results A total of 915 papers were collected in our research, including 901 foreign papers and 14 Chinese papers.Among 915 papers, there were 548 piece of original articles , and 175 piece of reviews;the most frequently cited paper was cited for 131 times.Major of those papers were focused on antimicrobial agents treatment for infec-tions and intracellular bacterial resistance mechanisms.Conclusion Researches on intracellular antimicrobial agents distribution have drawn great attention around the world and have been deeper in recent 20 years.

关 键 词：细胞内 抗菌药物 分布 文献研究 计量分析 

分 类 号：R978[医药卫生—药品] R969.3[医药卫生—药学]