品管圈在医院制剂生产质量持续改进中的应用与成效  

Application and Achievement of Quality Control Circle in Continuous Quality Improvement in the Production of Hospital Preparations

作　　者：李茜[1] 郑东升[1] 杭汉强[1] 张幸国[1] 

机构地区：[1]浙江大学医学院附属第一医院药剂科,杭州310003

出　　处：《中国药房》2014年第33期3112-3115,共4页China Pharmacy

基　　金：浙江省医药卫生科技计划项目资助(No.2010-KY101-083)

摘　　要：目的:通过品管圈活动持续改进医院制剂生产质量,缩短羟苯乙酯氯化钠溶液单位制剂生产时间。方法:遵循PDCA(Plan,Do,Check,Action)循环,按照品管圈的十大步骤进行质量持续改进,评价有形成果和无形成果。结果:针对羟苯乙酯氯化钠溶液的配制环节、灌装环节和人员因素,采用改进生产器械、更新设备、加大培训力度和考核以及优化生产流程的措施,缩短单位制剂生产时间21.15 min,目标达成率为133.9%,进步率为47.55%。在显著缩短单位制剂生产时间的同时,大幅度提高了圈员解决问题的能力、沟通与协调能力和工作的积极性(活动成长值正向增长分别为1.83、1.50、1.33)。结论:品管圈活动能有效提高医院制剂的生产效率,优化生产工艺和流程,推动医院制剂生产质量持续改进。OBJECTIVE： To improve the quality of hospital preparations production continuously, and to reduce the production time for unit preparations （PTUP） of Ethyl sodium chloride solution through quality control circle （QCC） activity. METHODS： In accordance with PDCA （plan, do, check, action） cycle and the ten steps of QCC, continuous quality improvement was conduct- ed, and tangible and intangible results were evaluated. RESULTS： Aimed at improving the preparation, filling and human factors, the PTUP of Ethyl sodium chloride solution was reduced for 21.15 min by means of improving production tools, updating equipment, strengthening training and assessment, as well as optimizing the production processes. The PTUP was shortened by 21.15 rain. The target achievement rate was 133.9%, and the rate of progress was 47.55%. The time of preparation production had been shortened greatly, at the same time, a substantial increase was observed in the problem-solving skills, communication and coordination ability and enthusiasm of QCC members （positive increase of growth value were 1.83, 1.50, 1.33）. CONCLUSIONS： QCC activity could effectively increase the production efficiency of hospital preparations, optimize production processes and procedures. and promote continuous quality improvement of the production of hospital preparations.

关 键 词：品管圈 PDCA循环 医院制剂 单位制剂生产时间 质量持续改进 

分 类 号：R95[医药卫生—药学]