外阴阴道假丝酵母菌感染菌种分布及耐药性分析  

Distribution and drug resistance analysis of vulvovaginal yeast infections

作　　者：康小平[1] 薛芹[1] 张鹏[1] 龙飞 

机构地区：[1]武汉科技大学附属天佑医院皮肤性病科,武汉430064 [2]武汉市第七医院皮肤性病科,武汉430071

出　　处：《中国性科学》2014年第8期3-5,共3页Chinese Journal of Human Sexuality

基　　金：湖北省科技计划自然科学基金项目(2011CDB242)

摘　　要：目的:分析我院外阴阴道假丝酵母菌感染分布特点及耐药性。方法:从我院2010年5月至2012年6月接诊的240例外阴阴道假丝酵母菌病患者取阴道分泌物做假丝酵母菌培养以及药敏试验。结果:本研究共分离出8种205株假丝酵母菌,检出率85.42%(205/240)。其中最多的是白色假丝酵母菌,以及热带假丝酵母菌和光滑假丝酵母菌,分别为53.7%(110/205)、19.5%(40/205)和10.2%(21/205),假丝酵母菌对两性霉素B和5-氟胞嘧啶的药物敏感性较好,但是对唑类药物的敏感性有所差异。结论:对外阴阴道感染假丝酵母菌患者进行真菌鉴定和药敏试验,可以指导临床用药,对临床药物治疗方面有着重要指导意义。To analyze the vulvovaginal yeast infection distribution and drug resistance of pa-tients in our hospital.Methods：Vaginal secretions samples of the 240 patients in our hospital from May 2010 -June 2012 were taken for Candida culture and sensitivity test.Results：In this study,eight kinds of 205 Candida were separated with a detection rate of 85.42%（205/240）.The detection rate of Candida albicans,Candida tropi-calis,and Candida glabrata were 53.7%（110/205）,19.5%（40/205）and 10.2%（21/205）respectively.Sen-sitivity of Candida yeast to amphotericin B and 5 -fluorocytosine drug was better,but the sensitivity to azoles was different.Conclusion：Fungal identification and susceptibility testing for patients with vulvovaginal candidiasis in-fection can guide the clinical medication,which is of important clinical significance.

关 键 词：假丝酵母菌 感染 耐药性 

分 类 号：R169[医药卫生—公共卫生与预防医学]