氧化钕-单壁碳纳米管修饰玻碳电极对鸟嘌呤和腺嘌呤的电催化氧化  

Electro-catalytic Oxidation for Guanine and Adenine of the Single-walled Carbon Nanotubes-Nd_2O_3 Modified Glassy Carbon Electrode

作　　者：张娜[1] 张克营[2] 耿涛[2] 李雪莲[2] 江涛[2] 张程[2] 方浩[2] 

机构地区：[1]安徽省宿州学院体育学院,安徽宿州234000 [2]安徽省宿州学院自旋电子与纳米材料安徽省重点实验室,化学与生命科学学院,安徽宿州234000

出　　处：《分析科学学报》2014年第4期529-532,共4页Journal of Analytical Science

基　　金：安徽省教育厅自然科学基金(No.KJ2012Z399);安徽省自然科学青年基金(No.1208085QB33);宿州学院科研平台开放课题(No.2012YKF05,No.2012YKF04,No.2013YKF22);宿州学院大学生科研立项项目(KYLXLKYB13-10)

摘　　要：制备了氧化钕-单壁碳纳米管修饰玻碳电极（Nd2O3-SWNTs/GCE）。采用循环伏安法（CV）探究了鸟嘌呤（G）和腺嘌呤（A）在该修饰电极上的电化学行为。结果表明：该修饰电极对G和A的氧化具有良好的电催化能力。在最佳条件下,用示差脉冲伏安法（DPV）对G和A进行检测,其氧化峰电流与浓度分别在10～50μmol/L范围内呈现良好的线性关系,检出限（S/N=3）均为5.0×10^-8 mol/L。该修饰电极可以用来同时测定DNA中的G和A。A single-walled carbon nanotubes-Nd2 O3 modified glassy carbon electrode was prepared. Cyclic voltammetry（CV） was used to investigate the electrochemical behavior of guanine and adenine on the modified electrode. The results indicated that the modified electrode showed a good electric catalytic ability for the oxidation of guanine and adenine. Differential pulse voltammetry was used to detect guanine and adenine. The oxidation peak current of guanine and adenine was linear with their concentration at the range of 10～50μmol/L,respectively with a detection limit of 5.0×10^-8 mol/L（S/N= 3）. The modified electrode can be used to simultaneously determine guanine and adenine in DNA.

关 键 词：氧化钕 单壁碳纳米管 鸟嘌呤 腺嘌呤 修饰电极 

分 类 号：O657.15[理学—分析化学]