微量元素硒的类胰岛素作用研究进展  

Research Progress on Insulin-mimetic Effects of Selenium

作　　者：计峰[1] 黄建国[1] 王雅蕾[1] 马春建[1] 苏琪[2] 

机构地区：[1]北京市农林科学院畜牧兽医研究所,北京100097 [2]中国农业科学院北京畜牧兽医研究所,北京100193

出　　处：《中国畜牧兽医》2014年第8期140-144,共5页China Animal Husbandry & Veterinary Medicine

基　　金：北京市农林科学院科技创新基金(CXJJ201317);北京市优秀人才培养(PYZZ13081301774)

摘　　要：近年来随着硒与糖尿病关系研究的不断深入,人们发现硒在促进细胞对葡萄糖的摄入、糖代谢以及信号传导等方面都具有类胰岛素作用,但其有效剂量接近于毒性剂量,故出于安全性的考虑并不适用于人体。作者在对硒的类胰岛素作用研究进行综述的基础上,深入探讨了硒在糖代谢中的调控机制,为利用硒调控畜禽应激状态下的糖代谢紊乱提供参考。During recent years,it has been found that selenium （Se） has insulin-mimetic effects on the promotion of glucose uptake into cells,glucose metabolism and signal transduction based on the relationship of Se and diabetes, but the effect dose of Se can only be obtained with nearly toxic doses and are not suitable for humans. This paper gives a brief review of research progress on insulin-mimetic effects of Se,in favor of an extensive study on the regulation mechanism of Se in glucose metabolism, so as to provide a reference for applying Se for regulation of disorders of glucose metabolism in stressed animals.

关 键 词：硒 胰岛素 葡萄糖代谢 

分 类 号：S816.72[农业科学—饲料科学]