正交设计优化百部多糖的超声提取工艺  

Study on the Extraction of Polysaccharides from Stemona by Ultrasonic Technology

作　　者：郭圣奇 覃茜柠 文全泰[1] 潘廷啟[1] 张照平[1] 黄锁义[3] 

机构地区：[1]右江民族医学院临床学院,广西百色533000 [2]右江民族医学院公共卫生与管理学院,广西百色533000 [3]右江民族医学院药学院,广西百色533000

出　　处：《化学世界》2014年第8期462-464,共3页Chemical World

基　　金：国家中医药管理局"十二五"中医药重点学科中药化学建设项目(国中医药人教发[2012]32号);广西重点学科药物化学(桂教科研[2013]16号);右江民族医学院民族医药协会资助项目(20120815)

摘　　要：用超声法对百部多糖进行提取,通过单因素和正交实验,研究料液比、超声功率、超声提取温度和超声作用时间的影响。其优化工艺条件为:料液比(g∶mL)1∶20,提取温度60℃,超声功率140W,作用时间20min,能使百部多糖的平均提取率为16.55%,RSD为0.22%。结果说明:超声波强化提取百部多糖过程简单,快捷和高效。The procedure of ultrasonic extraction of polysaccharide from Stemona was optimized. Through single factor experiment and orthogonal experiment, the effect of solid-liquid ratio, ultrasonic temperature, ultrasonic power and ultrasonic action time on polysaccharide extraction was studied as follows： The optimum ultrasonic extraction conditions were solid-liquid ratio （g ： mL）1 ： 20, temperature 60℃, ultrasonic power 140 W and ultrasonic action time 20 min. Under these conditions, the average extraction rate was 16.55%, and RSD was 0.22%. The preparative procedure is simple, quick and highly efficient.

关 键 词：百部 多糖 超声提取 正交设计 

分 类 号：R284.2[医药卫生—中药学]