罗红霉素在改性蒙脱土修饰电极上的电化学行为及测定  

Electrochemical Behaviors and Determination of Roxithromycin on Carboxymethylcellulose/montmorillonite Nanocomposite Modified Electrode

作　　者：李华刚[1] 吴洪梅[1] 罗宿星[1] 伍远辉[1] 

机构地区：[1]遵义师范学院化学化工学院,贵州遵义563002

出　　处：《化学世界》2014年第8期465-467,共3页Chemical World

基　　金：遵义市科技局资助项目(科合社字[2010]03);贵州省高校优秀科技创新人才支持计划(黔教合KY[2012]103)

摘　　要：制备羧酸甲基纤维素钠改性蒙脱土修饰电极(CMC-MMT/GC),研究罗红霉素在该电极上的电化学行为,以及缓冲溶液的pH值,罗红霉素的富集时间,电位等因素的影响,并用差分脉冲伏安法对其进行测定。结果表明:在最优化条件下,罗红霉素在5.73×10-4～1.08×10-2 mol/L范围内,氧化峰电流与其浓度呈现良好的线性关系,线性回归方程为Ip=-0.59157-0.13898c,相关系数R=0.99,检出限为1.05×10-4 mol/L。The electrode modified with sodium carboxymethylcellulose/montmorillonite nanocomposite was prepared, and the electrochemical behaviors of roxithromycin in the modified electrode were studied. The effects of pH value of buffer solution, preconcentration time and preconcentration potential were discussed. Determination of roxithromycin by differential pulse voltammetry was studied. Under the optimal conditions, the differential pulse voltammetric peak current had a good linear correlation with roxithromy- cin concentration in the range of 5.73 × 10^-4 mol/L to 1.08 × 10^- 2mol/L. The linear regression equation was Ip=-0. 59157-0. 13898c, correlation coefficient R=0.99, and the detection limit was 1.05× 10^-4mol/L.

关 键 词：罗红霉素 测定 电化学 修饰电极 

分 类 号：O641.4[理学—物理化学]