糖尿病对精神分裂症患者认知功能的影响  

Influence of Diabetes on Cognitive Function of Schizophrenia Patients

作　　者：敖磊[1] 何长江[1] 郭娟[1] 张丽[1] 

机构地区：[1]西安市精神卫生中心,陕西西安710061

出　　处：《昆明医科大学学报》2014年第9期109-112,共4页Journal of Kunming Medical University

基　　金：陕西省科学技术基金资助项目(2011k15-01-01)

摘　　要：目的研究糖尿病对精神分裂症患者认知功能的损害情况.方法对21例西安精神卫生中心合并糖尿病的精神分裂症患者与30例西安精神卫生中心无糖尿病及无糖耐量异常的精神分裂症患者采用PANSS量表及MCCB中10项认知功能量表评定分裂症患者临床症状,认知功能和生活质量.结果精神分裂症合并糖尿病的患者其处理速度、注意、工作记忆,执行功能和视觉记忆功能受损严重于分裂症患者(P<0.05),同时2组患者对比生活质量无明显改变(P>0.05).结论精神分裂症合并糖尿病患者比不合并糖尿病患者存在更严重的认知功能损害,提示治疗精神分裂症患者合并糖尿病可能有助于其认知功能的改善,但这一改变并不影响其生活状况.Objective To understand the influence of diabetes on cognitive function of schizophrenia patients.Methods 21 schizophrenia patients with diabetes and 30 schizophrenia patients without diabetes were enrolled in this study.PANSS scale and MATRICS Consensus Cognitive Battery were used to assess the clinical syndrome and to test the cognitive function of the enrolled patients.Results Impairment of processing speed,attention/working memory, executive function and visual memory in schizophrenia patients with diabetes was significantly severer than that of schizophrenia patients without diabetes（P〈0.05）. Conclusion The impairment of cognitive function in schizophrenia patients with diabetes was severer than schizophrenia patients without diabetes,which suggested that the prevention and management of diabetes may improve cognitive function of schizophrenia patients.

关 键 词：精神分裂症 糖尿病 认知功能 

分 类 号：R587.1[医药卫生—内分泌] R749.3[医药卫生—内科学]