综合护理干预对慢性丙型肝炎并发糖尿病患者的临床效果  

Comprehensive nursing intervention to improve quality of life in chronic hepatitis C patients with diabetes mellitus

作　　者：石慧芬 傅旭丹[1] 

机构地区：[1]义乌市中心医院内二科,浙江省义乌市322000

出　　处：《世界华人消化杂志》2014年第18期2617-2621,共5页World Chinese Journal of Digestology

摘　　要：目的:探讨护理干预提高慢性丙型肝炎(chronic hepatitis C,CHC)诱发糖尿病(diabetes mellitus,DM)患者生命质量的临床效果.方法:按照随机数字表法将92例CHC合并D M患者均分为实验组和对照组,两组患者均给予相同治疗方案,对照组患者采取常规护理,实验组患者采取综合护理,比较两组患者护理干预前后空腹血糖(fasting bloodglucose,FBG)、糖化血红蛋白(glycosylated hemoglobin,HbA1c)水平及生命质量评分.结果:两组患者护理干预后3、6 mo FBG水平均显著下降,与干预前比较(7.33 mmol/L±2.12 mmol/L vs 8.43 mmol/L±3.52 mmol/L,6.77 mmol/L±1.57 mmol/L vs 8.43 mmol/L±3.52 mmol/L;8.48 mmol/L±1.67 mmol/L vs8.55 mmol/L±3.65 mmol/L,7.68 mmol/L±1.50 mmol/L vs 8.55 mmol/L±3.65 mmol/L),差异具有统计学意义(P<0.05);实验组患者干预后3、6 mo FBG水平均显著低于对照组(7.33 mmol/L±2.12 mmol/L vs 8.48 mmol/L±1.67 mmol/L,6.77 mmol/L±1.57 mmol/L vs 7.68 mmol/L±1.50 mmol/L),差异具有统计学意义(P<0.05);两组患者护理干预后3、6 mo HbA1c水平均显著下降,与干预前比较(7.61%±2.18%vs 9.19%±3.53%,6.73%±1.38%vs 9.19%±3.53%;8.28%±2.45%vs9.16%±3.56%,7.73%±1.79%vs 9.16%±3.56%),差异具有统计学意义(P<0.05);实验组患者干预后3、6 mo HbA1c水平均显著低于对照组(7.61%±2.18%vs 8.28%±2.45%,6.73%±1.38%vs 7.73%±1.79%)(P<0.05),差异具有统计学意义(P<0.05);实验组患者护理干预后躯体功能、躯体角色、肌体疼痛、一般健康状况、生命力、社会功能、情感角色及心理健康评分均显著高于对照组(81.03±2.55 vs 79.63±1.25,50.68±2.78 vs 49.07±3.20,74.38±1.61 vs 73.27±1.53,37.86±1.34vs 36.87±1.22,65.46±0.81 vs 63.86±0.78,87.69±1.52 vs 85.78±1.28,53.59±3.31 vs47.47±3.60,75.74±1.87 vs 72.31±0.56),差异具有统计学意义(P<0.05).结论:综合护理干预能够有效改善患者FBG和HbA1c水平,提高生命质量,临床效果显著.AIM： To explore if comprehensive nursing intervention can improve quality of life in chronic hepatitis C（CHC） patients with diabetes mellitus（DM）.METHODS： Ninety-two CHC patients with DM were randomly divided into either an experiment group or a control group. The patients received the same treatments. The control group received routine nursing intervention, while the experiment group received comprehensive nursing intervention. Fasting blood-glucose（FBG）,glycosylated hemoglobin（HbA1c） and the quality of life（QOL） were compared between the two groups. RESULTS： In both groups, the levels of FBG at 3 and 6 mo after nursing intervention were significantly lower than those before nursing intervention（7.33 mmol/L ± 2.12 mmol/L vs8.43 mmol/L ± 3.52 mmol/L, 6.77 mmol/L ± 1.57 mmol/L vs 8.43 mmol/L ± 3.52 mmol/L; 8.48 mmol/L ± 1.67 mmol/L vs 8.55 mmol/L ± 3.65 mmol/L, 7.68 mmol/L ± 1.50 mmol/L vs 8.55 mmol/L ± 3.65 mmol/L, P〈0.05）. After nursing intervention, the levels of FBG at 3 and 6 mo in the experiment group were significantly lower than those in the control group（7.33 mmol/L ± 2.12 mmol/L vs 8.48 mmol/L ± 1.67 mmol/L, 6.77 mmol/L ± 1.57 mmol/L vs 7.68 mmol/L ± 1.50 mmol/L, P〈0.05）. In both groups, the levels of HbA1 c at 3 and 6 months after nursing intervention were significantly lower than those before nursing intervention（7.61% ± 2.18% vs 9.19% ± 3.53%, 6.73% ± 1.38% vs 9.19% ± 3.53%; 8.28% ± 2.45% vs 9.16% ± 3.56%, 7.73% ± 1.79% vs 9.16% ± 3.56%, P〈0.05）. After nursing intervention, the levels of HbA1 c at 3 and 6 mo in the experiment group were significantly lower than those in the control group（7.61% ± 2.18% vs 8.28% ± 2.45%, 6.73% ± 1.38% vs 7.73% ± 1.79%, P〈0.05）. After nursing intervention, the scores of physical performance, role-physical, bodily pain, general health, vitality, social function and role-emotional in the experiment group were significantly higher than those in the control group（81.03 ± 2.55 vs 79.63 ± 1.25, 50.68

关 键 词：护理干预 慢性丙型肝炎 糖尿病 生命质量 临床效果 

分 类 号：R473.5[医药卫生—护理学]