依折麦布联合氟伐他汀调脂治疗的临床研究  

Effect of Ezetimibe combinded Fluvastatin on dyslipidemia

作　　者：刘财德[1] 柳蕾[1] 王学栋[1] 王善贵[1] 郭英[2] 

机构地区：[1]潍坊医学院,山东潍坊261000 [2]潍坊医学院附属医院内分泌科

出　　处：《青岛医药卫生》2014年第4期252-253,共2页Qingdao Medical Journal

摘　　要：目的探讨依折麦布联合氟伐他汀治疗高脂血症的疗效。方法选取60例新诊断高脂血症患者随机分为治疗组和对照组,治疗组给予氟伐他汀加依折麦布,对照组仅单用氟伐他汀调脂治疗,治疗4周,观察两组调脂疗效。结果两组患者总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)都有所降低,高密度脂蛋白胆固醇(HDL-C)有所升高,治疗组效果更为明显,差异有统计学意义(P<0.05)。结论依折麦布联合辛伐他汀治疗高脂血症的临床疗效显著。Objective To investigate the effect of ezetimibe combinded fluvastatin on dyslipidemia. Methods A total of 60 subjects were enrolled and assigned to the treatment group（n = 30,re-ceived ezetimibe combinded fluvastatin）and the control group（n =30,received fluvastatin only）. Both groups were treated for 4 weeks,and the effect was analyzed.Results The levels of serum TC,TG,LDL-C and HDL-C in both group were significantly lower after treatment,especially the treatment group （P 〈 0.05 ）.Conclusion Ezetimibe combinded Fluvastatin shows significant effect on modifying hyperlipidemia.

关 键 词：依折麦布 氟伐他汀 高脂血症 

分 类 号：R589.2[医药卫生—内分泌]