安儿宁颗粒治疗小儿急性支气管炎(痰热咳嗽)的临床研究  

Clinical study of Anerning Granule in treating infantile acute bronchitis(cough due to phlegm heat)

作　　者：陈永辉[1] 陆宏进[1] 张琪[1] 

机构地区：[1]首都儿科研究所附属儿童医院,北京100020

出　　处：《中医儿科杂志》2014年第4期15-18,共4页Journal of Pediatrics of Traditional Chinese Medicine

摘　　要：目的观察安儿宁颗粒对小儿急性支气管炎的治疗效果。方法将128例痰热咳嗽型急性支气管炎患儿随机分为治疗组和对照组,治疗组86例口服安儿宁颗粒,对照组42例服用小儿肺热咳喘口服液。分别于治疗前、后观察患儿呼吸道主要症状(咳嗽、咳痰),肺部体征(干啰音、粗中湿啰音)以及症状综合评分并记录不良反应。结果安儿宁颗粒愈显率为72.09%,总有效率为94.19%,明显优于对照组的42.86%,80.95%,2组间比较差异有统计意义(P<0.05)。治疗组咳嗽症状、肺部干啰音和粗中湿啰音单项积分较对照组明显改善,2组间比较差异有统计意义(P<0.05)。2组患儿治疗后白细胞及CRP恢复正常比率差异无统计意义(P>0.05)。结论安儿宁颗粒治疗小儿急性支气管炎疗效好,尤其对于咳嗽症状及肺部体征的改善效果显著,且无不良反应,值得临床推广。Objective To observe the effect of Anerning Granule on infantile acute bronchitis. Methods 128 cases of acute bronchitis were randomly divided into treatment group（86 cases） and control group（42 cases）. Treatment group was given Anerning Granule, control group given infantile Feirekechuan oral liquid. Respiratory symptoms （cough, phlegm）, physical signs in the lung （rhonchi, coarse tales） , symptom scores and adverse reactions were recorded. Results Anerning Granule got a markedly effective rate of 72.09%, the total effective rate was 94.19%, significantly better than the control group 42.86%, 80.95%, with statistically significant difference between 2 groups （P〈0.05）. Symptoms of cough, lung rhonchi and coarse tales single integral in the treatment group were better than in the control group, with statistically significant difference between 2 groups （ P〈 0.05 ）. 2 groups in the white cells and CRP normal ratio showed no statistical significance （ P〉0.05 ）. Conclusion Anerning Granule can get good effect in the treatment of acute bronchitis especially for the cough symptoms and pulmonary signs with no adverse reaction, worthy of application.

关 键 词：儿童 急性支气管炎 安儿宁颗粒 咳嗽 

分 类 号：R256.11[医药卫生—中医内科学]