极端环境细菌Gracilibacillus ureilyticus抑菌活性物质的提取与分离  

Extraction and Separation of Antibacterial Active Substance Produced by Gracilibacillus Ureilyticus

作　　者：刘振华[1] 聂永芳[2] 周晨妍[1] 孙景博[1] 郭伟云[1] 

机构地区：[1]新乡医学院生命科学技术学院河南省医学遗传学与分子靶向药物高校重点实验室培育基地,河南新乡453003 [2]河南科技学院机电学院,河南新乡453003

出　　处：《化学与生物工程》2014年第8期34-36,53,共4页Chemistry & Bioengineering

基　　金：新乡医学院博士科研启动基金资助项目(100411)

摘　　要：研究了芽孢细菌Gracilibacillus ureilyticus抗白色念珠菌活性物质的提取分离,以洗脱液颜色和活性为评价指标,探讨了大孔吸附树脂脱色和离子交换树脂提取工艺条件,为极端环境细菌Gracilibacillus ureilyticus抑菌活性物质的进一步开发和利用奠定了基础。The antibacterial active substance was extracted and separated by macroporous adsorption resin decolorization and ion exchange resin extraction.Using the eluention color and activity as evaluation indexes,the process of decolorization and extraction were optimized.It provides foundation for devecopment and utilization of antibacterial active substance produced by Gracilibacillus ureilyticus .

关 键 词：抑菌活性物质 大孔吸附树脂 脱色 离子交换树脂 提取 

分 类 号：R284.2[医药卫生—中药学]