青少期应激:肝主疏泄调畅情志中枢机制研究新角度  

Adolescent stress: new perspective of the liver regulating central mechanism of emotional

作　　者：史亚飞[1] 郭丽丽[1] 吴皓萌[1] 徐志伟[1] 

机构地区：[1]广州中医药大学,广州510405

出　　处：《中国中医基础医学杂志》2014年第8期1069-1072,共4页JOURNAL OF BASIC CHINESE MEDICINE

基　　金：国家重点基础研究发展(973)计划项目子课题(2011CB505103);国家自然科学基金资助项目(81173144);广东省科技攻关项目(2012B031800206)

摘　　要：进一步寻求与中医理论更加契合的心理应激实验模型,深入探讨与下丘脑海马有密切联系的其他重要脑区作用通路是推动肝调畅情志中枢机制研究发展的关键路径。青少期应激效应在情志异常发病机制中显示出愈发重要的作用,从中医青少年"肝常有余"生理病理特性来看可以更"纯粹"地模拟肝失疏泄情志内伤的病证过程,5-HT能系统可能是应激应对能力受损并影响至成年的最主要通路,青少期应激可以为肝调畅情志中枢机制研究带来新思路。Based on previous studies, the research group recognize： seek further psychological stress model fit better with the theory of traditional Chinese medicine, and explore other important brain regions pathway which is associated with the hippocampus and hypothalamus are to promote the critical path of liver regulating central mechanism of emotional development. Adolescence stress effect in the pathogenesis of mental disorders plays an increasingly important role, from the youth ＂liver often be excessive＂ physiological and pathological characteristics of traditional Chinese medicine view can be more ＂purely＂ simulation liver failure catharsis emotional injuries during the certification process,5-HT system at this stage might be the main pathway to impact and impair the ability to cope with adolescence stress till adult stage. The adolescence stress can bring new ideas for studying central mechanism of liver regulating emotional.

关 键 词：青少期 应激 肝主疏泄 调畅情志 

分 类 号：R395[哲学宗教—心理学]